Robert Lustig

  • Professor of Pediatrics in the Division of Endocrinology at the University of California, San Francisco
  • Member of the Institute for Health Policy Studies

Credentials

  • M.D. degree
  • Board Certified in Pediatrics and Pediatric Endocrinology

Education

Affiliations

  • University of California, San Francisco
  • Institute for Health Policy Studies

Research Focus

  • Childhood obesity and metabolic syndrome
  • Neuroendocrinology, with a specific emphasis on the regulation of energy balance by the central nervous system
  • Public health policy and the impact of dietary sugar on health

Notable Publications

Connect

Key Contributions

  • Identified the harmful effects of excess sugar consumption on metabolic health, particularly its role in obesity and diabetes.
  • Advocated for public health policies that reduce the consumption of sugar and processed foods.

Other Resources

  • :
You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 0:00 0
“when you consume sugar you are poisoning your mitochondria sugar and cyanide do the same thing”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:15 0
“sugar is public enemy number one”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:44 0
“sugar actually poisons the mitochondria”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 3:48 0
“ultra processed foods are now 56 of the UK diet”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 7:40 0
“if you get people on a real food diet you can mitigate virtually any and all of their chronic diseases.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 8:14 0
“the majority of what we're buying to feed ourselves and our families is ultra-processed food whether it's here in the UK or with you in America and that is contributing to this tsunami of chronic ill health that we're seeing.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 10:09 0
“children are consuming about 35 ounces a day of sugar from various sources, which is about six times the amount of sugar that I did from that one coke and they're doing it every day instead of once a week.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 12:25 0
“the food industry replaced the fat with sugar, which led to products like Entenmann's fat-free cakes.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 13:45 0
“alcoholics pick up a whiskey and can't put it down and they need it three times a day”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 14:32 0
“the first pass effect, the stomach and intestine metabolize that alcohol before any of it ever gets to the liver”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 16:29 0
“it causes glycation, it causes oxidative stress, it causes mitochondrial dysfunction and basically drives insulin resistance”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 21:51 0
“this was exactly when the hormone leptin had been discovered. Leptin was discovered in 1994 and I was prepared for that discovery because I worked at Rockefeller University with the guys who discovered it, Jeff Friedman and Rudy Libel.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 22:41 0
“these kids must have leptin resistance. These kids can't see their leptin and the reason is because their hypothalamus is dead because we killed it because of the tumor or the surgery the radiation and so because they can't see their leptin their brain thinks they're starving.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 23:50 0
“we gave them a drug called octreotide, a drug that you know is used by endocrinologists to usually suppress growth hormone release but it also suppresses insulin release so we repurposed it and we gave it to these kids and lo and behold, they started losing weight.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 24:18 0
“they started exercising spontaneously. One kid started competitive swimming, two kids started lifting weights at home, one kid became the manager of his high school basketball team running around collecting all the basketballs.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 27:52 0
“instead of worrying about weight we worried about insulin we said get the insulin down any way you can and that's what my clinic became it became an insulin reduction clinic it didn't it wasn't a weight loss clinic it was an insulin reduction clinic and when we got the insulin down then they lost weight”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 28:58 0
“what do you think is the single most important environmental exposure that leads to obesity and metabolic syndrome”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 30:51 0
“fructose and alcohol are metabolized virtually identically”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 35:03 0
“we actually proved that the sugar industry put their thumb on the scale back in the 1960s to exonerate their product because there had been data that had been coming out at that point showing that sugar was not good for you”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 36:23 0
“sugar and alcohol I don't think people commonly would put the two things together”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 37:34 0
“you started running an insulin reduction clinic... we would get rid of 75 percent of the chronic disease in America and in the world”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 40:18 0
“protect the liver and feed the guts”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 42:44 0
“they all have a prevention”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 44:07 0
“by what you eat”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 47:51 0
“it's actually the modern food environments this highly ultra processed food that we are consuming in inordinate quantities is actually at the root cause and unless we deal with that as a root cause we're going to be struggling people are going to be suffering healthcare systems are going to be suffering and we're not going to get anywhere”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 50:09 0
“the reason is because they're eating real food”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 52:44 0
“your insulin is high because of processed food”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 53:06 0
“short chain fatty acids come from fiber consumption and of course ultra-processed food is devoid of fiber”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 54:43 0
“now i think when we're talking about foods i think we need to get clear on terminology for people who are listening and they think okay look i get this highly processed food is at the root cause of many of these chronic diseases”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 56:03 0
“what we did in our clinic to be effective and we actually studied this we published on it we validated it as an instrument”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 57:22 0
“we would explain insulin and we would show them how much sugar was in each of the things that they were getting at home and versus what was on the table”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:00:23 0
“real food is food that came out of the ground or animals that ate the food that came out of the ground”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:00:51 0
“food is inherently good it's what we do to the food that's not and that's the point i try to make in the book and i have an entire section on what we did to the food that actually turned it from food into poison”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:01:19 0
“let's take an apple class 1 on the nova system would be an apple class 2 on the nova system would be apple slices class 3 on the nova system would be apple sauce, unsweetened class 4 on the nova system would be an apple pie”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:01:45 0
“it turns out that only the class 4 foods are associated with chronic disease”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:02:19 0
“the addition of sugar and the removal of fiber”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:03:51 0
“you're flooding your liver and the goal is protect the liver”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:04:14 0
“a lot's been written about the microbiome”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:07:58 0
“fiber is not food for you fiber is food for your bacteria”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:08:11 0
“when we took the fiber out of the food to process it we are now depriving our bacteria of the food they need to be able to live in symbiosis with us and so those bacteria the good bacteria are dead the bad bacteria have taken over and the bad bacteria is sending all sorts of bad signals actually suppressing serotonin generation in in the intestine thereby reducing the retrograde transport of serotonin back up into the nucleus tract to solitarius and that's called depression.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:08:51 0
“because you're not feeding those bacteria that bacteria are basically stripping the mucin layer right off your intestinal epithelial cells because they can eat that and that's then exposing and denuding the your intestine and uh and making it uh uh you know all the junk that's in your intestine basically can get through called leaky gut contributing to inflam inflammation inflammatory bowel disease irritable bowel syndrome and um insulin resistance all because you didn't feed your gut.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:09:41 0
“the ultra processing of food is overwhelming the liver with sugar and it's starving the gut through its lack of fiber and then the consequences are the liver could be you know fatty liver type 2 diabetes but the problem when the the gut gets starved and as you say leaky gut or increased intestinal permeability sets in then you're opening up for everything autoimmune disease food allergies um alzheimer's depression all all these things have been associated with increased permeability in the gut.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:14:48 0
“you will see that different people thrive on different diets that's you know you you i i think real life clinical practice teaches you that well these guys here are literally rocking a low carb real food diet their markers look good their bloods look great and all these people here are doing great on a whole food vegan diet”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:15:18 0
“commonality is low sugar high fiber both diets work when they're low sugar high fiber”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:16:03 0
“so what happens with apple juice whether it's let's just let's just take apple juice that's not also uh sweetened right because you know sometimes they add extra sugar just taking an apple and putting it in the vitamix okay okay all right let's do that kind of apple juice okay apple juice that's been vitamix or the jamba juice okay people say that's great right because that's whole fruit well it was whole food now it's not”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:20:41 0
“so you've taken one of the two cardinal phenomena of health and you've basically thrown it in the garbage can”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:22:33 0
“you put something sweet on the tongue, message goes tongue to brain, sugar's coming message goes brain to pancreas, sugar's coming release the insulin. But then the sugar never comes because it was a diet sweetener.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:23:18 0
“all the studies of diet drinks show that caloric intake total caloric intake does not change. So you think you're doing well by taking 150 calories in sugar out of your diet, but it turns out you end up making up those 150 calories elsewhere in your diet.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:24:33 0
“we now know that certain diet sweeteners actually alter the microbiome in a negative fashion and contribute to leaky gut, the most famous of which is sucralose.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:26:10 0
“there was a paper that came out in the American General Clinical Nutrition about 2017. What they did was they showed we're using a meta-analysis that the toxicity of one Coca-Cola equals the toxicity of two diet Coca-Colas.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:29:18 0
“in fact you can basically put on about 10 kilos of subcutaneous fat before you will have over expanded those cells those cells will then have choked off and died will have released their grease into the area will have recruited macrophages in to clean up the grease and will then have released cytokines into the bloodstream which will by the way go into the systemic circulation so you have to have a lot of grease in order to get a hot concentration high enough to go back to the liver to activate the cytokine response than the liver and cause insulin resistance”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:30:15 0
“the visceral fat the belly fat okay the you know beer belly if you will fat right now that fat turns out not to be from beer that fat turns out to be from stress from stress you know a lot about stress that fat in your belly fat okay visceral fat is due to cortisol and cortisol is because our our world is now overly stressful and people are overly stressed like all the time”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:32:15 0
“the liver fat the fat in your liver turns out to be the most egregious because it's right there it's causing the problem right where the action is right there in your liver okay it turns out only a half a pound of visceral fat i'm sorry liver fat half a pound of liver fat and you will end up with metabolic dysfunction insulin resistance”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:32:49 0
“so the question is what makes the liver fat answer sugar because of this phenomenon the de novo lipogenesis that we've been talking about so you are mainlining it right into the organ that is the most susceptible to the problem”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:36:07 0
“sugar down regulates its own receptor on the tongue, so the more sugar the less sweet therefore you need more sugar so it becomes a vicious cycle.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:36:19 0
“it still causes liver fat accumulation in kids we you know now show have shown that 20 of children have liver fat unrelated to obesity.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:37:02 0
“sugar inhibits an enzyme in the brain in astrocytes called glutamine synthetase.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:37:32 0
“sugar's been associated with irritability, violent behavior, cognition problems, dementia in adults, changes in the prefrontal cortex thickness, problems in school.”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:42:56 0
“if you enjoyed that conversation all about the negatives of eating too much sugar”

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You’re Eating Too Much Sugar! – You May Never Eat It Again After Watching This | Dr. Robert Lustig
Impacts of Sugar Consumption on Health and Chronic Diseases Prevention 1:43:04 0
“we are actually all forming cancers in our body all the time but if you can prevent tumors from growing their blood supply you can actually keep these cancers harmless so this is what foods are able to do”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 0:14 0
“Dr. Robert Lustig is an endocrinologist that is he's a specialist in the function of hormones in the body and a professor of Pediatric Endocrinology at the University of California San Francisco he has authored more than 100 peer-reviewed studies exploring how different types of nutrients that is food impact our cellular functioning our organ functioning and thereby our health.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 0:38 0
“during today's discussion we discussed the idea of whether or not a calorie is indeed a calorie and whether or not our body weight and body composition only reflects the number of calories we eat versus the calories that we burn.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 0:51 0
“we talk about how different food types that is how the different macronutrients protein, fat and carbohydrates are processed in the body and the important role that fiber and the gut microbiome plays in that process.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:04 0
“and we pay particular attention to the topic of how different types of sugars and fructose in particular can indeed be addictive to the brain and can modify the way that hormones in the body in particular insulin impact our Liver Health Kidney Health and indeed the health of all of our cells and organs.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 5:32 0
“I love coffee I'm somebody that drinks coffee nearly every day usually about 90 to 120 minutes after I wake up in the morning although not always sometimes if I'm going to exercise I'll drink coffee first thing in the morning but I love love love coffee.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 8:32 0
“everyone thinks that obesity is about energy balance that is calories in calories out therefore two behaviors gluttony and sloth therefore if you're fat it's your fault therefore diet and exercise therefore any calorie can be part of a balanced diet therefore don't pick on our calories go pick on somebody else's calories.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 9:51 0
“you eat 160 calories in almonds how many of those do you absorb? 130. You eat 160 you absorb 130 where' the other 30 go? In the processing of that food energy.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 12:17 0
“so we all eat protein let's say you eat too much protein yeah you know the Porter House steak all right now if you're a bodybuilder those amino acids might go to muscle and you might increase your muscle mass because you're a bodybuilder because you're putting uh excess uh force on those muscles and you're growing those muscles okay but let's say you're not a bodybuilder let's say you're a mmortal like me or let's say you're a kid going through puberty who's synthesizing a lot of muscle not because they're lifting weights because they're because testosterone's making it happen yeah absolutely but let's say you're not let's say you know you're just you know just schlump the the street like uh you know joeo okay and you eat that Porter House you've taken on all these amino acids there's no place to store it other than muscle so your liver takes the excess and deamidates that amino acid takes the amino group off to turn it from a amino acid into an organic acid and then that organic acid can then enter the kreb cycle the tricarboxylic acid cycle what goes on in the mitochondria in order to…”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 17:19 0
“so over here we have omega-3s heart healthy anti-inflammatory anti-alzheimer's save your life and over here we have trans fats the devil incarnate consumable poison because you can't break the trans double bond you don't have the desaturates to break that trans double bond so it basically accumulates lines your arteries lines your liver causes chronic metabolic disease causes insulin resistance Omega-3s don't even get broken down for energy because they're so important they stay intact because your brain needs them your heart needs them whereas trans fats can't be broken down because of that trans double bond one save your life other one kill you they're both nine calories per gram if you explode them in a bomb calorimeter because a calorie burned is a calorie burned but a calorie eaten is not a calorie eaten because one will save your life one will kill you”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 18:34 0
“carbohydrates I think most of our audience will be familiar with the so-called macronutrients so we talked about fat in this case almonds there's some Fiber in there probably a little bit of carbohydrate a little bit little bit talked about the Porter House with butter right making me hungry already that's protein and fat MH very little of any carbohydrate it should be zero essentially maybe one zero zero yep um and then now we're talking about carbohydrates and we're going to subdivide that into glucose and fructose right galactose basically becomes glucose in the liver so we we can dispense with that unless you have a disease called galactosemia which is about one in 20,000 um and causes neonatal menitis and you know it's a disease as a pediatric endocrinologist I would take care of but we can dispense with that for the moment all right so glucose fructose glucose is the energy of life every cell on the planet Burns glucose for energy glucose is so damn important that if you don't consume it your body makes it so it will take an amino acid and turn it into glucose that's gluconeogenesis glucogenesis that's right it will…”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 25:03 0
“Berry it comes with a whole lot of fiber, in the banana comes with a whole lot less fiber, and in the Coca-Cola it doesn't come with any fiber, and the fiber is what mitigates the absorption.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 25:17 0
“When you consume the fructose with fiber, like your blueberries, you're feeding your microbiome. That fructose wasn't for you, got it, such a relief.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 26:43 0
“Fructose inhibits three separate enzymes necessary for normal mitochondrial function. Your mitochondria have to work at peak efficiency, that's what metabolic health is.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 31:45 0
“if you have obesity it's a 15-year longevity tax and if you have metabolic syndrome it's a 20-year longevity tax”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 31:53 0
“that is primarily not completely but primarily sugar it's also you know Omega sixes it's also so trans fats”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 32:36 0
“margarine was the bad guy without question”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 33:12 0
“you can make trans fats in your own kitchen by taking olive oil and heating it to beyond the smoking point”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 33:23 0
“sugar is the big problem because of these three enzymes that you are inhibiting”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 38:11 0
“65% of that which is ingested goes to resting energy expenditure just to power the body, 10% goes to the thermic effect of food, and then 25% goes to activity.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 38:59 0
“The higher your glucose goes the more your pancreas will release insulin in order to bring that glucose down.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 40:25 0
“Insulin is not the diabetes hormone, insulin is the energy storage hormone.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 42:02 0
“If you're active, then you will clear glucose into muscle. Therefore, your blood glucose won't rise as much because it went into muscle and therefore your pancreas will put out less insulin because it doesn't have to clear as much from the bloodstream.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 44:36 0
“insulin's actually making the kidney disease and so these animals that are insulin resistant they have diabetic nephropathy without diabetes so the insulin is having a negative clearly negative effect on the kidneys without binding to the receptor.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 45:08 0
“the point is insulin does stuff by itself and it turns out insulin drives growth.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 48:09 0
“oxygen is necessary for mitochondria to be able to burn in the absence of oxygen the cell only knows how to grow.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 50:26 0
“has there been any effort to treat tumors by oxygenating tumors yes and what does that look like it's hyperbaric oxygen therapy it's a thing.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 51:28 0
“if I eat 250 calories of glucose how much of that did I quote unquote actually eat how much is is used how much is used yeah let's assume that I'm I'm at my desk working or I'm walking around a little bit I'm not I'm not exercising hard in the in the subsequent hour”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 52:03 0
“the glucose has to be phosphorated so you're going to lose an ATP in the process so you're going to go ATP goes to ADP and then that ADP will go to a denzine monophosphate which will then go to im an ocol monophosphate which will then go to Uric acid”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 52:29 0
“uric acid can inhibit mitochondrial function and it can also inhibit endothelial nitric oxide synthese which is the enzyme in your vasculature that is your endogenous blood pressure lowerer”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 57:26 0
“fructose wants to be fat, fructose is the lipogenic substrate here we're not talking about body fat we're talking about fat molecules that can potentially be used as energy that's right triglyceride molecules.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 57:40 0
“10% of that fructose will be turned into triglyceride right in the intestine and be released into the bloodstream and it is the reason for a post prandial triglyceride response.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:00:00 0
“fructose nitrates tight Junction proteins causing them to be transiently permeable allowing some of the junk in your intestine to get through into your bloodstream.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:01:58 0
“fiber to build up this muin layer is one way to reinforce the the uh the fence that that is the tight junctions Etc exct um between your intestine and the bloodstream.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:03:52 0
“you have the probiotic which is the bacteria itself and you the postbiotic which is what the bacteria make in order to heal you okay and so short chain fatty acids are postbiotics”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:04:16 0
“if I consume fructose in the form of let's say a highly processed food has minimal antioxidants but it's got plenty of calories typically uh and it's disrupting the tight junctions making my gut leaky”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:05:07 0
“Andrew I am for dessert for dessert I am not for dessert for breakfast lunch snacks and dinner”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:05:41 0
“the National School breakfast program which 29% of school children today consume is a bowl of Froot Loops and a glass of orange juice that is 41 gam of sugar”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:10:45 0
“every cell in your body but especially your nerve cells, your neurons, relies on electrolytes in order to function properly so when you're well hydrated and you have the appropriate amount of electrolytes, your system, your mental functioning and your physical functioning is improved.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:11:50 0
“we talked about dessert for breakfast in the form of cereals some of which are um disguised or couched as healthier, you know I think of like Honey Nut Cheerios it seems healthier than Froot Loops it looks healthier like the just by way of color it looks kind of weedy you know color.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:13:33 0
“the grocery store bread had sugar added to it on purpose because when you bake it the sugar does not evaporate it stays in the bread and the sugar is hygroscopic meaning it holds on to water.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:17:05 0
“High fructose corn syrup is particularly egregious because it's so missable because it's already a liquid.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:19:23 0
“High fructose corn syrup... is causing metabolic illness disrupting mitochondria and on and on.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:23:52 0
“I consider myself pretty informed about nutrition and health but already today I've learned two dozen facts about processing of fructose and calories generally that I had no knowledge of prior.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:24:11 0
“Food science is what happens to food between the ground and the mouth, nutrition is what happens to food between the mouth and the cell, metabolic health is what happens to food inside the cell.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:24:30 0
“All of the chronic diseases that we are suffering from, like type two diabetes, hypertension, dyslipidemia, cardiovascular disease, cancer, dementia, fatty liver disease, polycystic ovarian disease, those eight diseases which make up 75% of healthcare expenditures in this country today are all inside the cell because they are all mitochondrial dysfunction.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:29:44 0
“Stanford University has to pay $2,750 per year in obesity related health care expenses that they have passed on to you even though you're not obese.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:30:46 0
“Diabetes is now 11.4% of America. 20 years ago it was about 8%.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:31:18 0
“Sugar and these hidden sugars in exactly that's right.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:32:23 0
“High fructose corn syrup and sucrose are no different metabolically.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:33:33 0
“Sugar inhibits burning it inhibits those three enzymes involved in mitochondrial function.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:36:08 0
“inevitably every one of those people is blown away by the fact that it works and assumes that it's all because of reduced calorie intake overall and they lose like anywhere from 30 to 55 lbs and keep it off and they like hey this is great actually still eat ribeye steaks and salads and but they're not eating croutons they're and so in some sense it looks extreme it sounds ketogenic but it's nothing like that you're just saying basically stay away from you're eliminating processed foods you're eliminating liquid calories in in general you and on and on so there's nothing sophisticated about it”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:37:08 0
“it's nothing to do with the calories it has everything to do with the insulin if you get the insulin down you're not shunting energy to Fat you can lose weight your fat will give up the ad the uh the the triglyceride stored in it as soon as your insulin goes down insulin is pushing on your fat cell all the time and as long as your insulin's up your fat cell can't release it the minute your insulin goes down you can now engage in what we call lipolysis hormone sensitive lipase is a an enzyme in the fat cell that is uh inhibited by insulin as soon as the insulin's gone hormone sensitive lipase can turn that stored triglyceride into free fatty acids and glycerol and release it and you can lose weight so get the insulin down and it all works”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:38:10 0
“what makes insulin go up well two things refine carbohydrate and sugar those are the two things that make insulin go up in addition Branch chain amino acids make insulin go up as well Lucine isoline veine which is in cornfed beef chicken and fish processed food”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:39:24 0
“my colleague Dr Carlos Montero who is a professor of Public Health at the University of sa Paulo has done the world a great service he has developed a system for categorization of food processing it is called the Nova System just means new but he has basically categorized every food anywhere in the world into one of four classes”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:42:32 0
“Co and what it is is it's a recommendation engine based on the science of human metabolism that categorizes Foods based on not their nutrient content but on their metabolic effect.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:43:24 0
“I'm not low carb I'm low insulin and there are a lot of ways to get to low insulin get rid of the refined carbohydrate get rid of the sugar increase the fiber get rid of the branch chain amino acids.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:43:37 0
“eating fish is a good place to be um even eating a steak is okay if it's a pasture-fed steak.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:44:43 0
“marbling is intramyocellular lipid that animal has metabolic syndrome the American cornfed animal because that corn is filled with Branch chain amino acids.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:46:03 0
“the whole egg near perfect protein score in terms of its bioavailability um eggs are terrific.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:46:48 0
“marine life is number one okay um you know fish provided you're not bringing in heavy metals with it.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:49:35 0
“Vitamin D deficiency is associated with all these chronic metabolic diseases however supplementation with vitamin D has not fixed any of those.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:50:33 0
“Vitamin D is a pre-pro hormone it's not active at all vitamin D is converted in the liver first step to a compound called 25 hydroxy vitamin D that is a pro hormone it also is inactive it has no activity whatsoever from there 25 hydroxy vitamin D can be metabolized one of two ways it can either be one alpha hydroxylated in the kidney to the active form one alpha one uh 25 dihydroxy vitamin D which will then do all of the business of vitamin D such as calcium absorption from the gut suppression of the immune system at the toll like receptor 4.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:52:40 0
“Reducing fructose intake the one of the primary ways to reduce systemic inflammation.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:53:43 0
“Improving sleep is there any evidence that you know chronic slight sleep deprivation can increase inflammation well what it will do is it'll increase cortisol and chronically increased cortisol will definitely lead to increased inflammation.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:55:17 0
“those require cortisol in order to manage and mitigate that stress the upcoming 2024 election that's chronic stress that is not acute stress”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:56:02 0
“how that chronic stress ultimately leads to metabolic and mental health disaster”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:56:13 0
“when I was growing up there were some kids in school that were overweight but it was the occasional kid right now it seems depending on where one draws the threshold for overweight it seems that there are a lot of kids that are overweight um how about 25% obese and 40% overweight”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:57:00 0
“Colorado was this um was this like like Beacon of of of fit people but now it's no longer and that's too oh okay cool I'll tell you why there there are four things that can increase mitochondrial uh uh uh biogenesis you going to tell me altitude is one cold yeah that's why Colorado is less obese altitude that's why Colorado is less obese”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:23:40 0
“for primary prevention the mean increase in lifespan for being on a Statin is four days.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:24:07 0
“for secondary prevention that's where Statin shine.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:24:19 0
“you need a lowfat diet and a priest.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:25:52 0
“the best way to reduce small dense LDL is to reduce insulin by reducing sugar.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:08:19 0
“the effective campaign to end smoking in young people was to hijack their inherent rebelliousness of Youth and then they were like no we're not going to stick it to them like you know the the as my friend calls it like the two the two-finger business card like No And so that worked that worked”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:10:03 0
“we've been able to actually look gestational diabetes way down, obesity down slightly not a lot but a little bit, cardiovascular disease down”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:12:04 0
“how did we solve those four no one could imagine that we would ever solve smoking right but we did sort of I mean we brought consumption down by half, that's pretty good when you think about it for an addictive substance how many fewer people are dying of lung cancer nowadays in the US um it's like 80% lower”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:35:26 0
“they say hey we'll do it for you we'll provide every kid in America with a nutritious meal Every Single Day hot lunch well they didn't say hot okay they just said lunch okay nutritious they said nutritious and I put that in air quotes too because it wasn't nutritious”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:17:54 0
“our kids are suffering under the weight the burden of this chronic disaster of ultra processed food which is not food and no wonder they're all obese and uh um uh sick and um uh you know doing so poorly in school and by the way also depressed”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:18:18 0
“Ultra processed food has now been shown in three separate studies to correlate with depression in teenagers”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:22:29 0
“how many pounds or kilos of big belly fat do you have to gain before you get metabolic leil I don't know but I'm guessing it's less than 22 pounds it's way less oh for once I got an answer right today that's right about five about five pounds”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:23:18 0
“the question is what made the visceral fat in the first place was it calories no it's cortisol it's stress it's the combination of the sympathetic nervous system and cortisol”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:24:07 0
“so when you have fat in your liver it causes metabolic dysfunction right away and the question is where did that fat come from that came from alcohol or sugar”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:28:21 0
“very famous study done in Copenhagen 100 normal individuals 25 in four different groups one group one liter of sugared soda per day for six months... gained 10 kilos... one group one liter of water per day for 6 months... lost two kilos... one liter of milk per day... no change... one liter of diet soda per day... gained two kilos.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:31:12 0
“the insulin response you put something sweet on the tongue message goes tongue to brain Sugar's coming message goes brain to pancreas through the vus nerve Sugar's coming release the insulin and so tongue doesn't know if it's sugar or not it releases the ins the pancreas releases the insulin which drives energy into fat whether it was you know from the diet sweetener or not.”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:34:20 0
“the company recognized that they wanted to be a metabolically healthy company and they knew they weren't they contacted me and said would you put together a scientific advisory team to advise us what we need to do to change the food in order to be a metabolically healthy company and we want to lead”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:37:01 0
“three principles if you adhere to these three principles you can turn any food healthy including Ultra processed food number one protect the liver number two feed the gut number three support the brain”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:38:14 0
“number one got to get rid of the sugar number two got to add fiber number three got to add Omega-3s number four got to do something about the emulsifiers”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:43:02 0
“so the question is what's addictive is fat addictive no because if fat was addictive then all the people on the Atkins diet or on the ketogenic diet would be gaining weight not losing it”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:44:18 0
“caffeine's a problem really caffeine's classic addictive substance at every level”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:46:19 0
“glp1 decreases the rate of gastric emptying that is its primary driver yes it does affect the brain I'm not arguing that it does but the primary effect is to reduce the rate of gastric emptying so you stay Fuller longer because the food doesn't move through the stomach”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:47:44 0
“comes in who's obese or slightly overweight right it's like I don't know what to do I'm trying to eat better exercise or a person comes in and says hey i' I've had a really hard time getting that last 20 9 PBS off for so many years will you prescribing those zic so the short answer is number one I'm retired so I'm not prescribing anything but let's let's let's go with there the data show that gp1 analoges like um semaglutide and now tepati which is uh Lily's version uh Manjaro is the diabetes version Z bound is the Obesity version the same way that OIC is the diabetes version for um uh novonordisk and woi is the Obesity version so they're all glp1 they're all G gp1 analog they synthesized in a lab it looks like glp1 smells like glp1 acts like G1 when injected tepati the uh Lily one actually has a dual function it uh binds to the Gip receptor so it might have double duty and the data show that it's actually even slightly more effective at Weight Loss than the Nova Nordisk version so we'll be seeing a shift in terms of uh…”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:54:19 0
“very promising a lot of people losing weight um cardiac issues very promising losing weight”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:54:53 0
“conversely if we just got sugar consumption down to USDA guidelines by basically you know putting some limits on how much added sugar the food industry can put into any given product like Froot Loops we could reduce weight by 29% and save $3.0 trillion”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:57:38 0
“what if somebody who's taking uh one of these analoges makes it a point to do resistance training and here you know you mentioned bodybuilders earlier I'm not I'm not suggesting they become bodybuilders but we now know and I think Peter Tia and others would agree that everybody should be doing some form of muscle loss offsetting resistance exercise”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:59:51 0
“fructose is was a driver of immune dysfunction if he got off you can tell him from me if he got off the sugar his psoriasis would get better his weight would get better his arthritis would get better and he could have then that jump start”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:00 0
“if one is fat long enough, it becomes increasingly hard to get to a healthy weight because of the way the neural circuitry is impacted”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:01 0
“leptin as we talked about briefly is the hormone that tells your brain you've had enough”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:02 0
“insulin inhibits leptin signaling and it does it at three separate places in the hypothalamus”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:03 0
“get rid of the refined carbohydrate and sugar”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:04 0
“glucose activates the basil ganglia... fructose basically stimulates the nucleus, the reward center”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:07:04 0
“the cigarette industry was guilty of applying people with an addictive substance”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:08:59 0
“fruit is fine fruit juice is not great”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:09:14 0
“brown rice because of the fiber white rice polished you know number one all the vitamin B1 gone and of course a much larger glucose Excursion that glycemic index thing which of course I hate is it's glycemic load that matters and that is a very high glycemic load so brown rice”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:10:00 0
“only 10% of the available tomato sauces out on the market don't have added sugar so you have to know which ones”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:10:36 0
“the best choice is the highest fiber breads”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:11:30 0
“it depends on where the meat came from it depends on whether it was pasture raised depends on whether it's organic or not if the animal was injected with antibiotics stay away from it because those antibiotics are in the meat they're going to basically sterilize your gut and then the bad bacteria are going to take over”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:11:58 0
“fermented foods short chain fatty acids all good”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:12:58 0
“I don't practice it but I am for it for the right patient turns out who's the right patient the patient with liver fat because the reason it works is because it gives the liver a chance to basically burn off the fat that it's stored”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:13:18 0
“soda got it it's definite no and I don't even have to ask about sugary soda because that's uh that that's basically just poison in a can”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:13:48 0
“food combinations are great if there's some Fiber associated with it so it comes back to fiber again”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:15:00 0
“we can reduce glucose absorption by 36% fructose absorption by 38% sucrose absorption by 40% simple starch absorption by 9% and increase short chain fatty acid production by 60% without an increase in gas”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:19:25 0
“get rid of the sugar okay period very clear”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:19:31 0
“number two go for a walk the exercise piece yeah go for a walk”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:20:15 0
“at UCSF we've gotten rid of all sugar beverages we have the healthy beverage initiative so no Coke machines at UC”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:20:52 0
“every hospital and really every public venue in America needs to clear out the junk”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:22:13 0
“every kid gets a hot meal made from scratch each day”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 3:24:02 0
“no greater than one teaspoon per serving no greater than four gram per serving of added sugars”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 2:06:55 0
“thank you for joining me for today's discussion with Dr Robert Lustig about nutrition and how sugar impacts the health of our brain and body”

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