A lipoprotein

A lipoprotein

A lipoprotein is a biochemical assembly whose primary purpose is to transport hydrophobic lipid (also known as fat) molecules in the water outside cells, where they cannot dissolve in their free form. They are complex particles composed of multiple proteins which, when bound to lipids, allow fats to move through the water inside and outside cells. Each type of lipoprotein has a specific density and function.

Category

Bioactive compound

Molecular Formula

Variable

Mechanism of Action

Lipoproteins transport lipids around the body in the extracellular fluid, making fats available to body cells for receptor-mediated endocytosis.

Evidence Grade

A

Other Names

• High-density lipoproteins (HDL)
• Low-density lipoproteins (LDL)
• Very low-density lipoproteins (VLDL)
• Intermediate-density lipoproteins (IDL)
• Chylomicrons

Primary Benefits

• Helps in the transportation of lipids throughout the body
• HDLs help reduce cholesterol levels
• LDLs provide the necessary cholesterol to cells

Recommended Dosage

Side Effects

• High levels of LDL can lead to plaque build-up and atherosclerosis

Precautions

• Individuals with high cholesterol or heart conditions should monitor lipoprotein levels

Interactions

• Interacts with dietary fats and cholesterol

Key References

• https://www.ncbi.nlm.nih.gov/books/NBK395573/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577766/