ALCAR

No summary available for this substance.

ALCAR

Acetyl-L-carnitine, also known as ALCAR, is an acetylated form of L-carnitine. It is naturally produced by the body, although it is often taken as a dietary supplement. ALCAR is believed to play a role in energy production by transporting fatty acids into the mitochondria where they can be burned up and used as fuel.

Category
Dietary Supplement
Molecular Formula
C9H17NO4
Mechanism of Action
ALCAR assists in the transport of fat into the mitochondria where it is oxidized and converted into ATP. It also enhances the production of acetylcholine, an important neurotransmitter for brain and nerve function.
Evidence Grade
B - Moderate evidence for efficacy

Other Names

  • Acetyl-L-carnitine
  • Acetylcarnitine
  • Acetyl carnitine

Primary Benefits

  • Enhances cognitive function
  • Aids in metabolic function
  • Boosts energy
  • Supports heart health

Recommended Dosage

Adult 500-2,000 mg per day
Children Not recommended for children

Side Effects

  • Nausea
  • Vomiting
  • Abdominal cramps
  • Diarrhea

Precautions

  • Pregnant or breastfeeding women should avoid
  • People with underactive thyroid (hypothyroidism) should avoid
  • People with a history of seizures should consult a doctor before use

Interactions

  • Anticoagulant or antiplatelet drugs
  • Acenocoumarol (Sintrom)
  • Warfarin (Coumadin)

Key References

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649700/
  • https://www.sciencedirect.com/science/article/pii/S0024320502028017
Cognitive decline is NOT inevitable: Dale Bredesen, M.D.
Prevent Cognitive Decline: Empower with Brain-Boosting Strategies & Tips 21:18 0
“Other people will notice it with things like taking some exogenous ketones or some coconut oil or something like that or some MCT oil or they will notice it with taking creatine that's another common one or ALCAR.”

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