Antacids
Antacids are over-the-counter medications used to neutralize stomach acid. They can help relieve symptoms of heartburn, acid reflux, and other stomach acid-related conditions. Antacids work by increasing the pH of stomach acid, which makes it less acidic and thus less irritating to the esophagus and stomach lining.
- Category
- Over-the-counter medication
- Molecular Formula
- Varies by type
- Mechanism of Action
- Antacids work by neutralizing stomach acid and raising the pH level in the stomach. The increased pH inhibits the action of pepsin, an enzyme involved in protein digestion that can be irritating to the stomach in the presence of excessive acid.
- Evidence Grade
- A
Other Names
- Acid reducers
- Acid neutralizers
Primary Benefits
- Relief from heartburn
- Reduction of acid reflux symptoms
- Soothing of stomach ulcers
Recommended Dosage
| Adults |
1-2 tablets every 4 to 6 hours |
| Children |
Doctor consultation advised |
Side Effects
- Constipation
- Diarrhea
- Nausea
Precautions
- Not recommended for prolonged use
- Check for sodium content if on a low-sodium diet
- Consult with a doctor if kidney disease is present
Interactions
- Reduces effectiveness of other medicines taken at the same time
- Can interfere with certain lab tests
Key References
- https://www.nhs.uk/conditions/antacids/
- https://www.mayoclinic.org/drugs-supplements/antacids-oral-route/description/drg-20070710
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