Ashwagandha

No summary available for this substance.

Ashwagandha

Ashwagandha, also known as Indian ginseng, is a medicinal herb that has been used in Ayurvedic medicine for thousands of years. It is considered an adaptogen, meaning it can help your body manage stress. Ashwagandha also provides numerous other benefits for your body and brain.

Category
Herbal supplement
Molecular Formula
C28H38O6
Mechanism of Action
Ashwagandha contains chemicals that might help calm the brain, reduce inflammation, lower blood pressure, and alter the immune system.
Evidence Grade
B

Other Names

  • Withania somnifera
  • Indian ginseng
  • Winter cherry

Primary Benefits

  • Reduces stress and anxiety
  • Improves brain function
  • Boosts immune system
  • Increases energy and stamina
  • Regulates blood sugar levels

Recommended Dosage

Adults 300-500 mg per day
Children Consult a healthcare provider

Side Effects

  • Diarrhea
  • Stomach upset
  • Vomiting
  • Decreased blood pressure

Precautions

  • Pregnancy
  • Breastfeeding
  • Auto-immune diseases
  • Surgery
  • Thyroid disorders

Interactions

  • Sedative medications
  • Immunosuppressants
  • Thyroid hormone pills

Key References

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/
How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried
Optimizing Women's Health: Hormones, Nutrition, Exercise, and Genetics Insights 1:36:53 0
“the moment you said lowering cortisol thought of the two supplements that come to mind are ashwagandha which I think can potently reduce cortisol but I've heard some recommendations about cycling it”

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How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried
Optimizing Women's Health: Hormones, Nutrition, Exercise, and Genetics Insights 1:39:45 0
“ashwagandha at least the time that I wrote that book ashwagandha's data is not great but lack of proof is not proof against”

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Female-Specific Exercise & Nutrition for Health, Performance & Longevity | Dr. Stacy Sims
Optimizing Women's Wellness Through Nutrition, Exercise, and Hormone Health 1:58:11 0
“looking at the different adaptogens ashanda is a good one holy basil or Tulsi is another one Shandra and then getting into some of your medicinal mushrooms Lions man Rishi those are the two big ones that I look to and often have women use”

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276 ‒ Special episode: Peter on longevity, supplements, protein, fasting, apoB, statins, & more
Longevity, Health Tools, Proactive Management: Nutrition, Exercise, Supplements, Genetic Insights 34:16 0
“I take 600 milligrams of ashwagandha... I take two grams of glycine... I take magnesium L3 and 8.”

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276 ‒ Special episode: Peter on longevity, supplements, protein, fasting, apoB, statins, & more
Longevity, Health Tools, Proactive Management: Nutrition, Exercise, Supplements, Genetic Insights 38:29 0
“I was not taking ashwagandha a year ago... I had taken it a long time earlier but just kind of came back to it probably found a slightly more potent version of it.”

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Boost Your Energy & Immune System with Cortisol & Adrenaline | Huberman Lab Essentials
Optimize Energy and Immunity Naturally with Hormone Regulation Practices 25:14 0
“one of the most common ones is ashwagandha it has a very strong effect on cortisol itself how strong the decrease in cortisol noted in humans is 14.5 to 27.9% reduction in otherwise healthy but stressed humans.”

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Dr. Peter Attia: Supplements for Longevity & Their Efficacy
Supplements, Lifestyle, and Strategies for Longevity and Optimal Health 2:16:40 0
“I take magnesium L3 and8 and ashwagandha for Sleep um i' take slow mag which is just a a magnesium chloride slow relasing version of magnesium and I take magnesium oxide so I take magnesium in three forms”

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