Bactrim

No summary available for this substance.

Bactrim

Bactrim is an antibiotic combination containing a sulfonamide antibiotic. It is commonly used to treat a variety of bacterial infections.

Category
Antibiotic
Molecular Formula
C14H18N4O3
Mechanism of Action
Bactrim works by inhibiting the production of folic acid in bacteria, which is essential for the synthesis of DNA, RNA, and proteins. The bacteria eventually die or are destroyed by the immune system.
Evidence Grade
A

Other Names

  • Co-trimoxazole
  • Septra
  • Sulfatrim

Primary Benefits

  • Treats bacterial infections
  • Treats urinary tract infections
  • Treats ear infections
  • Prevents certain types of pneumonia

Recommended Dosage

Adults 160mg/800mg every 12 hours
Children Based on weight (8mg/40mg per kg every 24 hours in two divided doses)

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Allergic reactions

Precautions

  • Avoid if allergic to sulfa drugs
  • Avoid in late pregnancy
  • Avoid if suffering from severe liver or kidney disease
  • Avoid if suffering from blood disorders

Interactions

  • Warfarin
  • Methotrexate
  • Phenytoin
  • Digoxin
  • Cyclosporine

Key References

  • https://www.ncbi.nlm.nih.gov/books/NBK547852/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1744559/
The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 10:18 0
“sulfur containing drugs like Bactrum for example is a very common one there's also others like Lasix and others that have sulfur those drugs are it's it's sort of it's a it's a man-made component of making these drugs so people tend to be more sensitive to the sulfur in those”

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