Bisphenol A (BPA)

Bisphenol A (BPA)

Bisphenol A (BPA) is an organic synthetic compound that is a colorless solid used primarily to make plastics and epoxy resins. It has been in commercial use since 1957. BPA-based plastic is clear and tough, and made into a variety of common consumer goods. BPA is also used in the synthesis of polysulfones and polyether ketones, as an antioxidant in some plasticizers, and as a polymerization inhibitor in PVC.

Category

Industrial Chemical

Molecular Formula

C15H16O2

Mechanism of Action

BPA is an endocrine disruptor. It can mimic the body's hormones, and it can interfere with the production, secretion, transport, action, function, and elimination of natural hormones. BPA can behave in a similar way to estrogen and other hormones in the human body.

Evidence Grade

A

Other Names

• Bisphenol A
• 4,4'-(propane-2,2-diyl)diphenol

Side Effects

• Hormonal imbalances
• Potential reproductive disorders
• Potential impact on brain development
• Potential risk for certain cancers
• Potential impact on heart health

Precautions

• Avoid use in infants and young children
• Pregnant and breastfeeding women should avoid exposure
• People with hormone-related conditions should avoid exposure

Key References

• https://www.niehs.nih.gov/health/topics/agents/sya-bpa/index.cfm
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774166/