BPC-157

No summary available for this substance.

BPC-157

BPC-157 is a synthetic peptide chain with a sequence of 15 amino acids. It is derived from a protective protein found in the stomach. It has potent healing and regenerative effects, and it's known for its ability to improve wound and tissue healing, help with inflammatory conditions, and promote gut and brain health.

Category
Peptide
Molecular Formula
C62H98N16O22
Mechanism of Action
BPC-157 works by modulating the release of nitric oxide and increasing the expression of growth hormone receptors. It also stimulates angiogenesis, the process through which new blood vessels form from pre-existing vessels.
Evidence Grade
C - Promising preliminary evidence, but more research needed

Other Names

  • Body Protective Compound 157
  • Pentadecapeptide

Primary Benefits

  • Promotes wound healing and tissue regeneration
  • Supports gut and brain health
  • Helps with inflammatory conditions

Recommended Dosage

Typical Dose 200-800 micrograms per day
Maximum Dose Not established

Side Effects

  • Nausea
  • Headache
  • Skin irritation at the injection site

Precautions

  • Not recommended for pregnant or lactating women
  • Consult with a healthcare provider before use if you have a medical condition or are taking medications

Interactions

  • No known significant interactions

Key References

  • Sikiric P, et al. The influence of a novel pentadecapeptide, BPC 157, on N(G)-nitro-L-arginine methylester and L-NAME-induced health and gastrointestinal tract failure. Eur J Pharmacol. 1997.
  • Sikiric P, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011.
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 0:50 0
“Dr. Conover's expertise is in the use of exogenous peptides for activating multiple pathways in the brain and body to augment health.”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 19:46 0
“bpc almost with every patient it is very anti-inflammatory right and so just from a very general perspective you know most people walking around who are adults you know they're stiff they're sore as they get older they work out we work with uh athletes of all levels there's that element of inflammation maybe they have some chronic disease diabetes heart disease autoimmune disease inflammation is Paramount we understand that and bpc I you know observed with so many patients where their inflammation comes down so they feel better they're not as stiff they're not as store their knee doesn't hurt as much their shoulder improved”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 22:52 0
“BPC157 strongly anti-inflammatory yes my understanding is it also may upregulate growth hormone receptors.”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 23:15 0
“If you combine it with BPC which upregulates the growth hormone receptor, you make the process of growth hormone binding more efficient so you get more out of it.”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 23:47 0
“BPC157 is a gut peptide so we don't have to worry about it being destroyed by the gut. Most peptides that go into the gut are broken down.”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 24:11 0
“Oral BPC is more effective there for conditions like Crohn's or ulcerative colitis, irritable bowel, leaky gut.”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 28:00 0
“I think that's where bpc shine that's certainly where it's been studied in animal studies and I know that because we can inject it directly into tendons which is unlike steroids we would never inject steroids into a tendon you damage the tendon bpc we mix with things like PRP prf which is play Rich fiber and a little bit different than PRP and you'll get healing within days like it's awesome.”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 28:50 0
“I have been concerned just personally about um gray Market sources that um contain contaminants and the fact that um many people are obtaining bpc 157 not from a physician not from a compounded Pharmacy but just kind of on quote unquote on the internet.”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 44:54 0
“there's a lot of interest in BBC 157 a lot of use of bpc157 the sources of bpc157 are now drying up”

No comments yet.

View all comments (0)
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 45:14 0
“pentad DEA arginate may be a good prescribed substitution for people that can benefit from bpc157 and a good starting dose so to make it really clear for people helpful 250 micrograms to 500 micrograms we're using 500 micrograms injected daily again we like Monday through Friday take the weekends off”

No comments yet.

View all comments (0)
Breaking Bad Habits & Living Your Best Life – Dr Andrew Huberman (4K)
Optimizing Health and Functionality Through Sleep and Rhythm Management 2:44:21 0
“I've been experimenting with bpc 157 for which there are basically zero human data tons of animal data and anyone that's taking BBC 157 by the way you don't want to take it continuously and if you're going to take it get it from a compounding pharmacy and get it prescribed by a doctor because there's a lot of contaminated versions out there I would never take an oral version it can cause angiogenesis growth of of blood vessels so if you have a tumor you could cause angiogenesis of the tumor so um but I do take I was taking it um subq yep and I do heal noticeably faster when taking bpc157”

No comments yet.

View all comments (0)
Breaking Bad Habits & Living Your Best Life – Dr Andrew Huberman (4K)
Optimizing Health and Functionality Through Sleep and Rhythm Management 2:46:19 0
“many athletes used and use bpc 157 to recover from injury more quickly”

No comments yet.

View all comments (0)
Breaking Bad Habits & Living Your Best Life – Dr Andrew Huberman (4K)
Optimizing Health and Functionality Through Sleep and Rhythm Management 2:47:12 0
“taking bpc157 or injecting testosterone cp8 because you just want more gains than recover in the gym is absolutely foolish”

No comments yet.

View all comments (0)
Breaking Bad Habits & Living Your Best Life – Dr Andrew Huberman (4K)
Optimizing Health and Functionality Through Sleep and Rhythm Management 2:47:48 0
“bpc 157 the angio enic effects are really the most concerning again you could get vascularization of tumors”

No comments yet.

View all comments (0)
Dr. Peter Attia: Exercise, Nutrition, Hormones for Vitality & Longevity
Optimizing Health and Longevity Through Nutrition, Hormones, and Exercise 1:51:43 0
“I have no idea if stem cells work. I have no idea if BPC-157 works. I have no idea, frankly, if PRP even works, though it might seem to have some efficacy and some indications.”

No comments yet.

View all comments (0)