CRP

No summary available for this substance.

C-Reactive Protein

C-Reactive Protein (CRP) is not a supplement but a marker of inflammation in the body that is often measured in blood tests. It is produced in the liver and its levels rise in response to inflammation. High levels of CRP are associated with an increased risk of various chronic diseases, including heart disease and diabetes. It is not consumed as a supplement but can be influenced by diet, exercise, and certain medications.

Category
Biological marker
Molecular Formula
C203H343N61O63S6
Mechanism of Action
CRP is an acute-phase protein that binds to phosphocholine expressed on the surface of dead or dying cells in order to activate the complement system via the C1Q complex.
Evidence Grade
N/A

Other Names

  • CRP
  • High-sensitivity C-reactive protein
  • hs-CRP

Precautions

  • CRP levels should be monitored regularly in individuals with chronic inflammatory conditions
  • People at risk for cardiovascular disease may need to monitor their CRP levels

Interactions

  • Certain medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) and statins can lower CRP levels

Key References

  • Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation. 2003;107(3):499-511.
The Secret Power of Fasting for Longevity and Healing | Dr. Valter Longo
Unlocking the Connection Between Nutrition, Fasting, and Lifespan Benefits 1:11:56 0
“the blood for example part of the inflammation right the consequence you say dysfunction inflammation well I should go back to normal if if whatever intervention you use is working whether your insulin resistant dysfunctional marker or you have CRP that is high or you have interleukin 6 that is high exact Sarah they should be moving back to normal.”

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Dr Sampson: Your Oral Microbiome Can Be Deadly! I Cured Their Gum Disease And They Walked Again!
The Vital Link Between Oral Health and Overall Well-being 32:23 0
“another study also showed that when you treated someone's gum disease their levels of CRP significantly reduced.”

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Dr. David Sinclair: The Biology of Slowing & Reversing Aging
Strategies to Slow Aging and Optimize Health for Longevity 1:17:09 0
“I've got the InsideTracker data. So I pull that up on the screen, and I'm showing him the changes in my cholesterol and my CRP, which is inflammatory marker as you know.”

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Dr. David Sinclair: The Biology of Slowing & Reversing Aging
Strategies to Slow Aging and Optimize Health for Longevity 1:19:34 0
“CRP is something that we don't hear enough about, I think. Maybe, what do you know about CRP that I don't, I'm guessing a lot, but. Oh, it was originally picked up as something that was associated with heart disease in the Framingham study, I believe.”

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