Glutathione

No summary available for this substance.

Glutathione

Glutathione is an important antioxidant in plants, animals, fungi, and some bacteria and archaea. It is capable of preventing damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals.

Category
Antioxidant
Molecular Formula
C10H17N3O6S
Mechanism of Action
Glutathione neutralizes harmful free radicals and reactive oxygen species, and can regenerate other antioxidants in the body. It also binds to and detoxifies heavy metals and xenobiotics.
Evidence Grade
C

Other Names

  • GSH
  • L-Glutathione
  • Reduced Glutathione

Primary Benefits

  • Helps in detoxification
  • Supports immune system
  • Reduces oxidative stress

Recommended Dosage

Average Adult 500-1000mg per day
Maximum 2000mg per day

Side Effects

  • Abdominal cramps
  • Bloating
  • Trouble breathing
  • Allergic reactions

Precautions

  • People with asthma should use with caution
  • Should be avoided in pregnancy and breastfeeding
  • Long-term use can cause zinc deficiency

Interactions

  • May decrease effectiveness of chemotherapy drugs
  • May interfere with certain blood tests

Key References

  • Pizzorno, J. (2014). Glutathione!. Integrative Medicine (Encinitas, Calif.), 13(1), 8–12.
  • Wu, G., Fang, Y. Z., Yang, S., Lupton, J. R., & Turner, N. D. (2004). Glutathione metabolism and its implications for health. The Journal of nutrition, 134(3), 489–492.
Peptide & Hormone Therapies for Health, Performance & Longevity | Dr. Craig Koniver
Exploring Peptides, Hormones, and Therapies for Health and Wellness 59:35 0
“reduce those mercury levels which included limiting my tuna consumption because I'd been eating a lot of tuna while also making an effort to eat more leafy greens and supplementing with Knack and acetal cysteine both of which can support glutathione production and detoxification and worked to reduce my mercury levels”

No comments yet.

View all comments (0)
Using Your Mind to Control Your Physical Health & Longevity | Dr. Ellen Langer
Enhancing Health Through Mindfulness, Placebos, Sleep, and Exercise Strategies 1:17:45 0
“more leafy greens and supplementing with Knack and acetal cysteine both of which can support glutathione production and detoxification”

No comments yet.

View all comments (0)
Peter Attia, M.D. on Macronutrient Thresholds for Longevity and Performance, Cancer and More
Exploring Diet, Genes, and Aging for Longevity and Health 55:13 0
“They're both thermodynamically favorable, they allow glucose sparing, they allow glucose to then be used to make glutathione, which is important in the brain when you have damage.”

No comments yet.

View all comments (0)
How to Increase Your Speed, Mobility & Longevity with Plyometrics & Sprinting | Stuart McMillan
Enhance Movement, Power, and Health with Plyometric and Sprinting Exercises 1:13:15 0
“making an effort to eat more leafy greens and supplementing with Knack and acetylcysteine both of which can support glutathione production and detoxification”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 0:16 0
“every single cell in our bodies contains GL trium it's manufactured by our liver but I feel like it's the mother of all antioxidants that most people have never heard of”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 4:24 0
“the reason we don't talk about GL even though we have known for Glu for over 100 plus years is we have never figured out how to get inside your body so even though we inject it take a pill or inhale like I have a lot of athletes uh they'll inhale a gluathione or they may do a suppository or whatever you right whatever whatever they so they vaporize itap nebulize it and so they think that they're getting into the system but it's not there”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 5:02 0
“the Glon uh and and you said right now most of the people have not heard about it because of the fact that people do not understand what it is and how to deliver that part but you talking about Middle America but even people that have very affluent we were recently at one of the award shows and literally 90% of the people these are high power CEOs have never heard of glue iron before and I was shocked to see that wait a second you have all the resources in the world yet you have no idea GL is”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 7:02 0
“gluathione actually helps with phase one phase two detoxification Pathways for making sure it activates the liver and basically helps get rid of all the chemicals we exposed to.”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 9:15 0
“the body activates those systems to produce gione now it needs three things right three amino acids M two enzymes and a catalyst like selenium to produce one molecule of gluathione.”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 10:31 0
“if you take too much glutathione you'll reduce your endogenous production the liver production of glutathione or that you should cycle on and off of glutathione supplements.”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 13:03 0
“if you just take the three amino acids as glutathione and you swallow it or you take it in a liposomal version or a sublingual version or what have your body's actually not receiving that glutathione your glutathione production may rise but that's because that glutathione is being metabolized in the liver assembled back into those three amino acids and return to the bloodstream as glutathione.”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 15:52 0
“I had to put a chemical cap on it because if I put any of the caps on it it just destroys the whole molecule and that's why all this all this eons of research on gluathione nobody could figure out how a chemical cap on it.”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 31:18 0
“the indication is for skin lightning is that so that's something that came out of the Asian market and theyve been injecting GL with vitamin C every week injections for skin lightning and it worked it it does work”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 31:46 0
“somebody that's really dark pigmented could use high dose glutathione and vitamin C to actually lighten their skin”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 32:03 0
“when you use topical glow it didn't seem it doesn't seem healthy yeah it seem but if you use a topical version what it's actually doing is is removing all the de breeze out so if if you have those U oxidized U lipids on your skin that's com all the dark spots and when when that goes neutralized the skin gets all fair”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 33:36 0
“we have substantial albeit anecdotal evidence that it's very effective um because we'll we'll pull Labs on patients sometimes 10 to 12 weeks apart and we'll see patients with severely elevated liver enzymes and they respond very well to glutathione”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 34:42 0
“most people only need about 100 to 200 milligrams per day tce a day that's all they need 100 to 200 milligrams a day um trans dermal trans dermal okay compared to two two to 10 grams of IVs right it's it's is barbaric right and IV is Not Practical either”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 55:49 0
“a daily regular dose 200 milligrams of glutathione applied topically day or night is not going to have any long-term detriment effects on endogenous production”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 56:15 0
“this topical version if you take too much of it it's straight available bi available to your body... your body can actually go from oxid stress state to the opposite which is reductive State and so that is not healthy.”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 1:05:24 0
“we had done a 34 patient trial we were hired by this company out of Japan they wanted to do a heavy metal detox Japan has a lot of metal toxicity even today's State and so they wanted to do something with gluathione to do a detox studies of course everything passed only thing they could not pass is who's going to apply this stuff sticky stuff on the arms every day so they kind of I would if I had heavy metal toxicity especially in my brain yeah I'm bathing it you know.”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 1:09:46 0
“glutathione would result in less sick cells metabolically six cells”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 1:11:20 0
“how many people get to see on the other side of chemo healthy functioning with no side effects”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 1:15:21 0
“the GL Revolution why it is truly a revolution because if you understand what Glen does glut thing is just empowering your body it's just empowering your body to do what it's supposed to do and when you do that part you're not solving the problem for the body you're just giving the ammunation so the body's going to do everything on its own you're just hey just feeding them with the nutrients that the body needs and just sit back and relax and enjoy the body.”

No comments yet.

View all comments (0)
Dr. Nayan Patel: Unlocking Glutathione Your Body’s Super Antioxidant | TUH #057
Exploring the Vital Role of Glutathione in Health and Wellness 1:23:30 0
“Especially for those of you that have the MTHFR gene mutation or other gene mutations that interrupt glutathione pathways and cellular waste elimination.”

No comments yet.

View all comments (0)
What Is A Compounding Pharmacy? The Secret to Beating Illness & Hormone Imbalances | Shaun Noorian
Understanding Hormone Imbalances and Medication Applications for Optimal Health 57:34 0
“glutathione for detoxification and then a whole series of amino acids and minerals to help with also detoxification”

No comments yet.

View all comments (0)
The Shady Reality of the $Billion Supplement Industry | The Dr. Hyman Show
Understanding Supplement Quality, Nutrition Myths, and Modern Health Realities 1:03:39 0
“One of the things I test for is glutathione. Which is a really important compound that's involved in detoxification. It's involved in regulating immune function, inflammation.”

No comments yet.

View all comments (0)
The Shady Reality of the $Billion Supplement Industry | The Dr. Hyman Show
Understanding Supplement Quality, Nutrition Myths, and Modern Health Realities 1:04:16 0
“An acetylcysteine is a compound that boosts glutathione. There's also other things like lipoic acid and you wouldn't know this.”

No comments yet.

View all comments (0)
The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 0:00 0
“what alphalapoic acid can do is that it helps in that mitochondria it helps neutralize free radicals directly and then at the same time it recycles your major antioxidants your glutathione your vitamin C your vitamin E”

No comments yet.

View all comments (0)
The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 0:13 0
“it also upregulates another pathway called the NRF2 pathway the NRF2 pathway is the pathway that helps you produce more glutathione in your brain as well”

No comments yet.

View all comments (0)
The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 3:55 0
“alphalopoic acid is one of the unsung antioxidants out there people have heard of glutathione and vitamin C and vitamin E alphalapoic acid is actually the one that recycles all of those to make them more effective in the body”

No comments yet.

View all comments (0)
The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 5:15 0
“alphalapoic acid can do is that it helps in that mitochondria it helps neutralize free radicals directly and then at the same time it recycles your major antioxidants your glutathione your vitamin C your vitamin E it also upregulates another pathway called the NRF2 pathway”

No comments yet.

View all comments (0)
The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 10:33 0
“some people will be more sensitive to sulfur containing uh things like glutathione or like alphapoic acid and they may get more sulfur-l like symptoms of sometimes in people can cause some oxidative stress itself”

No comments yet.

View all comments (0)
Joe Rogan Experience #1735 – Peter Attia
Nutrition, exercise, genetics, disease prevention, and health discussion highlights. 2:50:11 0
“the cocktail that i used the the what i called the kitchen sink was monoclonal antibodies ivermectin um iv drips with a high dose of vitamin c glutathione zinc and then i did nad every other day”

No comments yet.

View all comments (0)