HCG

No summary available for this substance.

HCG

Human Chorionic Gonadotropin (HCG) is a hormone that supports the normal development of an egg in a woman's ovary, and stimulates the release of the egg during ovulation. It is used to cause ovulation and to treat infertility in women, and to increase sperm count in men. It is also used in young boys when their testicles have not dropped down into the scrotum normally.

Category
Hormone
Molecular Formula
C1105H1770N318O336S26
Mechanism of Action
HCG binds to the LH/CG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy, causing it to secrete the hormone progesterone. Progesterone enriches the uterus with a thick lining of blood vessels and capillaries so that it can sustain the growing fetus.
Evidence Grade
A

Other Names

  • Human Chorionic Gonadotropin
  • Chorionic Gonadotropin

Primary Benefits

  • Supports ovulation
  • Treats infertility in women
  • Increases sperm count in men
  • Helps in testicular descent in boys

Recommended Dosage

Type Dose varies significantly depending on the specific use case, typically administered under medical supervision

Side Effects

  • Headache
  • Irritability
  • Restlessness
  • Depression
  • Fatigue
  • Swelling
  • Allergic reactions

Precautions

  • Pregnancy
  • Prostate cancer or other androgen-dependent neoplasms
  • Current or previous thromboembolic disorders
  • Multiple pregnancies

Interactions

  • Gonadotropin-releasing hormone
  • Follicle stimulating hormone

Key References

  • https://www.ncbi.nlm.nih.gov/pubmed/620323
  • https://www.ncbi.nlm.nih.gov/books/NBK279054/
How to Increase Your Speed, Mobility & Longevity with Plyometrics & Sprinting | Stuart McMillan
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“a lot of guys in their teens 20s and 30s are taking testosterone when they don't need it it does shut down sperm production unless they're offsetting that with HCG or something like that and um they may think they don't want kids now but they may want them later and some permanent damage can be done”

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Breaking Bad Habits & Living Your Best Life – Dr Andrew Huberman (4K)
Optimizing Health and Functionality Through Sleep and Rhythm Management 2:47:24 0
“you need to bank sperm if you want kids, you need to take HCG if you want to maintain sperm production”

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Dr. Peter Attia: Exercise, Nutrition, Hormones for Vitality & Longevity
Optimizing Health and Longevity Through Nutrition, Hormones, and Exercise 1:47:36 0
“So it's going to crush endogenous luteinizing hormone levels, right, because it's-”

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Dr. Peter Attia: Exercise, Nutrition, Hormones for Vitality & Longevity
Optimizing Health and Longevity Through Nutrition, Hormones, and Exercise 1:57:19 0
“I would hope you would be steered toward HCG to at least preserve testicular function.”

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