Lasix
Lasix, also known as furosemide, is a potent diuretic used in the treatment of swelling and fluid retention caused by various medical problems, including heart, kidney, and liver disease. It belongs to a class of drugs known as loop diuretics, which work by causing the kidneys to get rid of unneeded water and salt from the body into the urine.
- Category
- Diuretic
- Molecular Formula
- C12H11ClN2O5S
- Mechanism of Action
- Lasix works by inhibiting the sodium-potassium-chloride cotransporter in the thick ascending limb of the loop of Henle, increasing the excretion of sodium, chloride, and water, thereby reducing blood volume and decreasing blood pressure.
- Evidence Grade
- A
Other Names
Primary Benefits
- Treats fluid retention
- Helps control high blood pressure
Recommended Dosage
| Adults |
20 mg to 80 mg daily |
| Children |
Depends on body weight |
Side Effects
- Dehydration
- Electrolyte imbalance
- Low blood pressure
- Hearing loss
Precautions
- Monitor electrolyte levels
- Not recommended for patients with severe kidney impairment
- Use cautiously in elderly patients
Interactions
- Aminoglycoside antibiotics
- Corticosteroids
- Certain blood pressure medications
Key References
- https://www.mayoclinic.org/drugs-supplements/furosemide-oral-route/description/drg-20071829
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