Magnesium

No summary available for this substance.

Magnesium

Magnesium is an essential dietary mineral and the second most prevalent electrolyte in the human body. Magnesium deficiencies are common in developed countries. A deficiency increases blood pressure, reduces glucose tolerance and causes neural excitation.

Category
Mineral
Molecular Formula
Mg
Mechanism of Action
Magnesium plays an important role in a wide range of fundamental biological reactions. It serves as a cofactor for more than 300 enzymes involved in processes like protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation.
Evidence Grade
A

Other Names

  • Magnesium cation
  • Mg
  • Magnesium element

Primary Benefits

  • Helps increase energy
  • Calms nerves and anxiety
  • Treats insomnia
  • Helps with digestion by relieving constipation
  • Relieves muscle aches and spasms
  • Regulates levels of calcium, potassium and sodium
  • Prevents migraine headaches
  • Helps prevent osteoporosis

Recommended Dosage

Adults 310-420 mg per day
Children 80-240 mg per day

Side Effects

  • Diarrhea
  • Nausea
  • Stomach cramps

Precautions

  • People with kidney disease should not take magnesium supplements without a doctor's supervision
  • High doses could be harmful
  • May affect some antibiotics' effectiveness

Interactions

  • Bisphosphonates
  • Antibiotics
  • Diuretics
  • Proton pump inhibitors

Key References

  • https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455825/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786912/
How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried
Optimizing Women's Health: Hormones, Nutrition, Exercise, and Genetics Insights 25:46 0
“micronutrients play a huge role in terms of hormone production magnesium you know the Magnesium is hugely involved in the way that you get rid of estrogen as an example so micronutrient testing what I usually do is a combination of blood and urine and so I'm looking at all of the micronutrients that we can measure that have some clinical scientific basis behind them”

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How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried
Optimizing Women's Health: Hormones, Nutrition, Exercise, and Genetics Insights 38:33 0
“I'm looking at some of the Minerals, Magnesium is really the most important and we know that somewhere around 70 to 80% of Americans are deficient in magnesium.”

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How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried
Optimizing Women's Health: Hormones, Nutrition, Exercise, and Genetics Insights 2:02:09 0
“the oral contraceptive depletes certain micronutrients so magnesium there's certain vitamin BS that are depleted uh it also affects the microbiome that data is not as strong but there seems to be some effect and there's also an increased risk of inflammatory bowel disease in autoimmune condition it increases inflammatory tone”

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Female-Specific Exercise & Nutrition for Health, Performance & Longevity | Dr. Stacy Sims
Optimizing Women's Wellness Through Nutrition, Exercise, and Hormone Health 29:47 0
“if you're getting that real food in then you're also getting you know your magnesium and your potassium and your sodium and all the things that people supposedly lose and you're able to also repair a lot better.”

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Dr. Peter Attia on Mastering Longevity – Insights on Cancer Prevention, Heart Disease, and Aging
Proactive Health Strategies: Preventing Chronic Conditions Through Lifestyle Choices 34:01 0
“if you had an apob level below about 30 mg per deciliter, it wouldn't be possible to develop atherosclerosis.”

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276 ‒ Special episode: Peter on longevity, supplements, protein, fasting, apoB, statins, & more
Longevity, Health Tools, Proactive Management: Nutrition, Exercise, Supplements, Genetic Insights 30:27 0
“I take slow mag... I'm trying to get up to about a gram of total magnesium or Elemental magnesium in my system a day.”

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276 ‒ Special episode: Peter on longevity, supplements, protein, fasting, apoB, statins, & more
Longevity, Health Tools, Proactive Management: Nutrition, Exercise, Supplements, Genetic Insights 34:16 0
“I take 600 milligrams of ashwagandha... I take two grams of glycine... I take magnesium L3 and 8.”

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Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients
Understanding Nutritional Essentials for Optimal Health and Longevity 10:09 0
“Zinc is in 2000 enzymes that have zinc fingers or otherwise need zinc. And magnesium's in 500 enzymes or so. Every DNA repair enzyme has magnesium in it.”

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Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients
Understanding Nutritional Essentials for Optimal Health and Longevity 31:20 0
“You need to eat your greens to get vitamin K and magnesium in the center of the chlorophyll”

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Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients
Understanding Nutritional Essentials for Optimal Health and Longevity 39:27 0
“Nature has conveniently colored it green for you because it's in plants. And so eat something. Eat a plate of spinach or kale or whatever, a couple often, because you need to get your magnesium.”

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Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients
Understanding Nutritional Essentials for Optimal Health and Longevity 39:52 0
“Plus, genetics is really important, too. So if you have a polymorphism, an alternate form of some gene, that means that you need more magnesium than the next fellow or more vitamin D than the next fellow, then you'll wanna know that.”

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Sleep, Daylight Anchoring, and Effects on Memory & Obesity with Dan Pardi
Understanding the Connection Between Sleep, Light, and Health Outcomes 53:41 0
“again, B6 affects the conversion of tryptophan into serotonin, which then gets converted into melatonin, and magnesium affects the conversion of serotonin into melatonin, and it's a GABA agonist.”

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Rhonda Patrick at Orthomolecular Medicine Congress in Bussum, Netherlands (Keynote Oct. 3rd, 2015)
Optimizing Health Through Micronutrients: Key Role in Disease Prevention 3:21 0
“around 70% of the population does not meet the requirement for vitamin D around 60% does not meet the requirement for vitamin E 45% does not meet the requirement for magnesium.”

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Rhonda Patrick at Orthomolecular Medicine Congress in Bussum, Netherlands (Keynote Oct. 3rd, 2015)
Optimizing Health Through Micronutrients: Key Role in Disease Prevention 6:02 0
“magnesium is required for over 300 different enzymes in the body and those enzymes include um those that are important for the production of ATP which is the energetic currency of the cell.”

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Rhonda Patrick at Orthomolecular Medicine Congress in Bussum, Netherlands (Keynote Oct. 3rd, 2015)
Optimizing Health Through Micronutrients: Key Role in Disease Prevention 8:14 0
“these DNA repair enzymes actually require magnesium as a co-factor to function without magnesium these DNA repair enzymes do not work efficiently”

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Rhonda Patrick at Orthomolecular Medicine Congress in Bussum, Netherlands (Keynote Oct. 3rd, 2015)
Optimizing Health Through Micronutrients: Key Role in Disease Prevention 17:02 0
“Eat Your Greens magnesium is high in spinach and kale and other green leafy vegetables um vitamin K calcium vitamin C um this is me drinking my my vegetable smoothie that I drink almost every day which has kale and spinach and charred and and more vegetables.”

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How to Improve Your Mobility, Posture & Flexibility | Dr. Kelly Starrett
Optimize Health Through Exercise, Nutrition, and Recovery for Better Well-being 1:20:19 0
“It's also important that you get adequate electrolytes. The electrolytes sodium, magnesium, and potassium are vital for the functioning of all the cells in your body, especially your neurons or your nerve cells.”

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How to Control Hunger, Eating & Satiety | Huberman Lab Essentials
Understanding Hormonal Influence on Hunger, Satiety, and Metabolic Health 32:02 0
“It also contains electrolytes so we meaning our neurons and our brain run on a variety of factors electrical activity and chemical transmission Etc but they require adequate levels of sodium potassium and magnesium.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 15:51 0
“Let's go over those four supplements again. Vitamin D, magnesium, iodine. What was the fourth one? And omega-3 fatty acids.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 49:31 0
“I mean, that's very subjective. I can't say I've noticed a specific difference with sleep when I've done that but let's talk everything magnesium and how you feel about that as a supplement.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 50:11 0
“The family gets up in the morning and you go hunt for wild plants that you know are safe. And wild plants are rich in magnesium. Cultivated, farm sourced produce is very low in magnesium. Typically 80% to 90% less magnesium than wild plants.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 50:40 0
“So we rely on magnesium supplementation to compensate for the deficiencies of water and plants, produce. Now, the form of magnesium, I think is a bit overblown.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 50:51 0
“Magnesium citrate is better as a laxative. So if you have some constipation issues, irregularity issues, magnum citrate is a good one, but they are in multiple good forms.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 51:33 0
“So no wheat, no grains. You don't bind magnesium anymore. Eating better food, like organic food, a little bit higher in magnesium.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 51:57 0
“Magnesium is a major constituent of your bones. It's also a major player in heart rhythms and blood pressure.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 52:45 0
“In this case, magnesium sulfate. You can give megadose because there's no diarrhea. Oral magnesium gives you diarrhea, but you can give megadose intravenous because it doesn't go through the gastrointestinal tract.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 1:03:48 0
“Magnesium. Big role restoration of lactobacillus reuteri a big role via oxytocin. Restoration of other healthy gut microbes, other lactobacilli, bifidobacteria species that enhance calcium absorption.”

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Leading Cardiologist: Your Doctor Is WRONG About Cholesterol | Dr. William Davis
Challenging Health Myths: Nutrition, Heart Health, and Gut Microbiome Insights 1:05:57 0
“So bone broth that is prolonged boiling of the bones and the addition of vinegar to mobilize minerals. It does mobilize some minerals, like calcium, magnesium, but it also releases the lead.”

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Gary Brecka: The TRUTH About Biohacking, Light Therapy, and Nutrients
Optimizing Health: Lifestyle, Nutrition, Sleep, Exercise, and Social Connections 30:46 0
“if you were to take a cup and scoop it out of a running stream and you were to analyze what's in that water you would find high mineral content first of all and not just potassium and magnesium and sodium the big ones that are in most electrolyte supplements you would find all of the other Trace metal Boron zinc selenium manganese”

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Dr. Jessica Peatross: Detoxing From Environmental Mold, Lyme Disease, and Parasites | TUH #157
Understanding Health, Nutrition, and Environmental Toxins for Holistic Wellness 15:15 0
“Sleep Breakthrough combines the power of magnesium with other natural ingredients to help us fall asleep faster, stay asleep longer, and actually wake up feeling refreshed.”

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The Shady Reality of the $Billion Supplement Industry | The Dr. Hyman Show
Understanding Supplement Quality, Nutrition Myths, and Modern Health Realities 15:34 0
“When you look at the amount of deficiencies, whether it's, you know, 90 plus% deficient omega-3, 80 plus insufficient, deficient in vitamin D, and some people say even more, magnesium is about 45%, zinc's about 40%. Iron, you know, we have a lot of of deficiencies.”

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The Shady Reality of the $Billion Supplement Industry | The Dr. Hyman Show
Understanding Supplement Quality, Nutrition Myths, and Modern Health Realities 18:02 0
“I gave her she needed like a thousand or more milligrams of magnesium to get her going and clear everything out. And that cured her migraines.”

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The Shady Reality of the $Billion Supplement Industry | The Dr. Hyman Show
Understanding Supplement Quality, Nutrition Myths, and Modern Health Realities 31:28 0
“I was in the hospital for a back surgery recently and you know I I was taking painkillers which can make you constipated so I wanted magnesium and I said to the the attending physician I said you know I want to get magnesium said sure and he wrote an prescription what are you what are you ordering he said well it's this such product I said that's magnesium oxide that's so poorly absorbed and it's also something that doesn't work for constipation that well I said how about magnesium citrate and he's like oh he looked it up and he's like oh Right.”

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The Shady Reality of the $Billion Supplement Industry | The Dr. Hyman Show
Understanding Supplement Quality, Nutrition Myths, and Modern Health Realities 38:24 0
“We check your magnesium level. We check your level of B vitamins like homocysteine and methylmalonic acid which measure B12, folate, B6 effectiveness. We measure omega-3s. We measure vitamin D. We can measure zinc. We can measure copper. We can measure iodine.”

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The Shady Reality of the $Billion Supplement Industry | The Dr. Hyman Show
Understanding Supplement Quality, Nutrition Myths, and Modern Health Realities 57:33 0
“It's a very calming neurotransmitter, helps with preventing anxiety and and I actually use a product, it's a metagenic product called Tranor for a lot of patients which has tr torine, magnesium, B6, a lot of things are very helpful in calming the nervous system which you know a lot of people have a lot of anxiety and it's and often you know Part of the problem is we deplete our nutrients under stress.”

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The Shady Reality of the $Billion Supplement Industry | The Dr. Hyman Show
Understanding Supplement Quality, Nutrition Myths, and Modern Health Realities 1:03:05 0
“Oh, I took magnesium or I took zinc or I took here's what happened to me.”

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This Food Reversed My Immune Age by 47% in 90 Days
Enhancing Health Through Lifestyle, Diet, and Environmental Choices 49:55 0
“that's rich in nutrients like zinc and magnesium that is important for function of your T cells and your natural killer cells and even has antimicrobial properties that are antiviral.”

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The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 12:08 0
“magnesium 3enate that has the highest amount of magnesium that gets in the system when you take it”

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The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 12:53 0
“magnesium is responsible for thousands probably enzyatic reactions in the brain so one of the major things that it does is helps relax the nervous system or relax the brain does that by increasing the conversion of a neurotransmitter called glutamate which is our primary excitatory neurotransmitter to GABA”

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The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 15:13 0
“magnesium as I mentioned has you know hundreds if not thousands of of important roles in the nervous system in the brain it's also visodilator as well also you can use magnesium to help you know dilate blood vessels a little bit on these at high doses for you know in IV for things like preeacclampsia you know in women but at lower doses it's still a vasoddilator”

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The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 16:11 0
“magnesium um in general mineral content of our food is down dramatically over the last 70 to 80 years and so it's hard to get enough magnesium in your diet but typically this is going to be in um it would be in plants ideally because plants would have minerals but you don't get as much as you used to so you can get it from meat obviously you can get it from um from mineral water”

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The 5 Compounds that Detoxify & Protect the Brain (neuroprotectants) – Dr. Sherr
Understanding the Visual Programming Language Processing for Creative Expression 16:45 0
“for magnesium meate I take 4 to 600 milligrams at night um you know sometimes I'll take more like the thing I like d magnesium melee because it's a little bit slower absorbing so I'm not going to like if I do go up north of 800 milligrams i'm not seat belted to the toilet you know I feel like it's it's I don't really have an issue maybe slightly looser stools but nothing insane”

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The Truth About Creatine & Exercise! 30% Of People Will Die From This! The Healthy Ageing Doctor
Optimize Your Health: Essential Insights on Nutrition, Exercise, and Hormones 1:04:13 0
“vitamin D as well as crucial isn't it for bone health I was reading that there it is it is magnesium vitamin D magnesium uh lesser known things strontium zinc Boron and micronutrients but big thing vitamin D magnesium”

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Dr. Peter Attia: Improve Vitality, Emotional & Physical Health & Lifespan | Huberman Lab Podcast
Improving Healthspan Through Lifestyle Choices and Preventive Health Measures 2:20:35 0
“there's tons of supplements that I think about when it comes to brain health you know what about thumin what about magnesium with L3 and8 the transporter um what about methylated vitamins that lower homocysteine what about EPA and DHA.”

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Dr. Peter Attia: Supplements for Longevity & Their Efficacy
Supplements, Lifestyle, and Strategies for Longevity and Optimal Health 2:16:40 0
“I take magnesium L3 and8 and ashwagandha for Sleep um i' take slow mag which is just a a magnesium chloride slow relasing version of magnesium and I take magnesium oxide so I take magnesium in three forms”

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Dr. Peter Attia: Supplements for Longevity & Their Efficacy
Supplements, Lifestyle, and Strategies for Longevity and Optimal Health 1:41:58 0
“before sleep I take magnesium 3 and8 I'm really bullish on magnesium as well appenine 50 milligrams which is essentially chamomile extract and theanine and occasionally I'll take 900 milligrams in netl also um or instead I kind of mix those up and around”

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Dr. Peter Attia: Supplements for Longevity & Their Efficacy
Supplements, Lifestyle, and Strategies for Longevity and Optimal Health 2:25:32 0
“everything we have talked about on this podcast today whether it be NR NAD nmn thumin magnesium this supplement that supplement all of that stuff while potentially mattering I would put in the category of was the Titanic serving LOB Lobster or steak”

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How to Exercise & Eat for Optimal Health & Longevity | Dr. Gabrielle Lyon
Optimizing Health and Longevity Through Nutrition, Exercise, and Supplements 2:50:12 0
“magnesium supplementation can be very beneficial for muscle for brain.”

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Dr. Rhonda Patrick: Micronutrients for Health & Longevity | Huberman Lab Podcast #70
Optimizing Health and Longevity Through Nutrients and Lifestyle Choices 1:40:43 0
“I do think magnesium is important in there as well. I mean, I think, again, about 40% of the US population doesn't get enough magnesium. It's an essential mineral we're supposed to be getting from our diet.”

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Dr. Rhonda Patrick: Micronutrients for Health & Longevity | Huberman Lab Podcast #70
Optimizing Health and Longevity Through Nutrients and Lifestyle Choices 1:42:30 0
“Well, magnesium is at the center of a chlorophyll molecule. Chlorophyll is what gives plants their green color. So dark, leafy greens are high in magnesium.”

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Dr. Rhonda Patrick: Micronutrients for Health & Longevity | Huberman Lab Podcast #70
Optimizing Health and Longevity Through Nutrients and Lifestyle Choices 1:42:54 0
“So dark, leafy greens are how I like to get my magnesium. I think it comes along with all these other important. I mean, you get calcium in them. You get vitamin K1.”

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Dr. Rhonda Patrick: Micronutrients for Health & Longevity | Huberman Lab Podcast #70
Optimizing Health and Longevity Through Nutrients and Lifestyle Choices 1:44:31 0
“But I also do supplement with magnesium. So supplementation with magnesium, it can cause GI distress at high doses. I personally like to take around 130 or 135 milligrams.”

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Dr. Rhonda Patrick: Micronutrients for Health & Longevity | Huberman Lab Podcast #70
Optimizing Health and Longevity Through Nutrients and Lifestyle Choices 1:46:04 0
“I take malate because I was told that it would be helpful. First of all, it doesn't make me sleepy like some of the other forms of magnesium, which act as a mild sedative for me.”

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Dr. Rhonda Patrick: Micronutrients for Health & Longevity | Huberman Lab Podcast #70
Optimizing Health and Longevity Through Nutrients and Lifestyle Choices 1:49:05 0
“I take a supplement called Magnesi-Om by Moon Juice. It's like a little powder. It's got a little bit of monk fruit, but it tastes good.”

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Dr. Rhonda Patrick: Micronutrients for Health & Longevity | Huberman Lab Podcast #70
Optimizing Health and Longevity Through Nutrients and Lifestyle Choices 1:49:13 0
“I do it a little bit before bedtime as well.”

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How Vitamin D, Omega-3s, & Exercise May Increase Longevity | Dr. Rhonda Patrick
Essential Insights for Health and Longevity Through Diet and Lifestyle 8:35 0
“And magnesium is an essential, essential mineral. About 50% of the US population does not basically get adequate intake of magnesium.”

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How Vitamin D, Omega-3s, & Exercise May Increase Longevity | Dr. Rhonda Patrick
Essential Insights for Health and Longevity Through Diet and Lifestyle 13:11 0
“But I also do a supplement of about 125 milligrams of magnesium and I do magnesium glycinate.”

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How Vitamin D, Omega-3s, & Exercise May Increase Longevity | Dr. Rhonda Patrick
Essential Insights for Health and Longevity Through Diet and Lifestyle 13:46 0
“Also, when I sauna, when I'm physically active, I also drink electrolytes after that. And that's another. So you can have an electrolyte drink that replaces some of the lost sodium and magnesium potassium, for example.”

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The Most Important Daily Habits For Health & Longevity – Dr Rhonda Patrick (4K)
Essential Omega-3 for Health, Longevity, and Disease Prevention Strategies 36:51 0
“magnesium is a perfect example half the country doesn't get enough magnesium which is about 320 milligrams for women and 420 for men”

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The Most Important Daily Habits For Health & Longevity – Dr Rhonda Patrick (4K)
Essential Omega-3 for Health, Longevity, and Disease Prevention Strategies 37:14 0
“you're not going to be repairing damage to your DNA and DNA damage is a major major cause of oncogenic mutations these are mutations that lead to cancer”

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The Most Important Daily Habits For Health & Longevity – Dr Rhonda Patrick (4K)
Essential Omega-3 for Health, Longevity, and Disease Prevention Strategies 38:36 0
“vegetables particularly leafy greens are really high in magnesium, they're high in calcium, they're high in vitamin K, they're high in folate”

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