Methylated vitamins

Methylated Vitamins

Methylated vitamins are versions of vitamins that have undergone a process called methylation, which makes them more easily absorbed and used by the body. They are particularly helpful for individuals with certain genetic mutations (like the MTHFR mutation) that affect the body's ability to convert traditional vitamins into their active or 'usable' form.

Category

Vitamins

Molecular Formula

Varies by vitamin

Mechanism of Action

Methylated vitamins are already in their active form and can be directly used by the body without needing conversion. This improves bioavailability and efficacy, especially in individuals with certain genetic mutations.

Evidence Grade

B

Other Names

• Activated Vitamins
• Methyl Vitamins

Primary Benefits

• Improved vitamin absorption
• Support for individuals with MTHFR mutations
• Support for brain health
• Prevention of homocysteine buildup

Recommended Dosage

Side Effects

• Nausea
• Cramps
• Diarrhea
• Allergic reactions

Precautions

• Those with a history of allergic reactions should use caution
• Not recommended for those with Leber's Disease
• Consult with a healthcare provider before use if pregnant or breastfeeding

Interactions

• Antacids and some medications can decrease absorption
• Excessive intake can interfere with certain medications

Key References

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707683/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312744/