Mulberry leaf extract
Mulberry leaf extract is derived from the leaves of the mulberry tree, a plant native to Asia. It has been used in traditional medicine for centuries, particularly in China, for its anti-inflammatory, antioxidant, and anti-diabetic effects. It is rich in beneficial compounds such as flavonoids, alkaloids, and anthocyanins.
- Category
- Herbal Supplement
- Molecular Formula
- Varies based on the specific compounds present
- Mechanism of Action
- The active compounds in mulberry leaf extract, including flavonoids and alkaloids, exert their effects through various mechanisms. They can inhibit carbohydrate-digesting enzymes, reducing the absorption of glucose from the gut, thereby controlling blood sugar levels. Additionally, they have antioxidant properties that help protect cells from oxidative damage.
- Evidence Grade
- C
Other Names
- Morus alba leaf
- White Mulberry leaf extract
Primary Benefits
- Blood sugar control
- Antioxidant effects
- Anti-inflammatory effects
Recommended Dosage
| Adults |
500 mg to 2,000 mg per day, typically taken before meals |
| Children |
Not recommended for children without medical advice |
Side Effects
- Mild gastrointestinal upset
- Allergic reactions in people sensitive to mulberry
Precautions
- Should be used with caution in people with diabetes as it can affect blood sugar levels
- Pregnant or breastfeeding women should consult with a healthcare provider before use
Interactions
- May enhance the effects of anti-diabetic medications
Key References
- Andallu, B., & Varadacharyulu, N. C. (2003). Antioxidant role of mulberry (Morus indica L. cv. Anantha) leaves in streptozotocin-diabetic rats. Clinica Chimica Acta, 338(1-2), 3-10.
- Kimura, T., Nakagawa, K., Kubota, H., Kojima, Y., Goto, Y., Yamagishi, K., . . . Oita, S. (2007). Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. Journal of Agricultural and Food Chemistry, 55(14), 5869-5874.