NAD booster
NAD boosters are a category of supplements designed to increase the levels of NAD+ (nicotinamide adenine dinucleotide), a crucial coenzyme found in every cell in the body. NAD+ plays a key role in cellular metabolism and energy production and is thought to decline with age.
- Category
- Nutritional supplement
- Molecular Formula
- Varies based on specific compound
- Mechanism of Action
- NAD boosters increase the levels of NAD+ in the body. NAD+ is a cofactor in many important enzymatic reactions, including those involved in metabolism and DNA repair.
- Evidence Grade
- C
Other Names
- Nicotinamide riboside
- Nicotinamide mononucleotide
Primary Benefits
- May improve cellular health
- May support healthy aging
- May enhance energy metabolism
- May enhance cognitive health
Recommended Dosage
| Typical Dosage |
300 mg |
| Maximum Dosage |
500 mg |
| Frequency |
Daily |
Side Effects
- Nausea
- Fatigue
- Headache
- Stomach discomfort
Precautions
- May lower blood pressure, caution for those with low blood pressure
- Not recommended for pregnant or breastfeeding women without medical advice
Interactions
- May interact with blood pressure medications
- Potential interaction with diabetes medications
Key References
- Trammell, S.A., et al. (2016). Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nature Communications, 7, 12948.
- Martens, C.R., et al. (2018). Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nature Communications, 9(1), 1286.
