Nicotine gums

Nicotine gums

Nicotine gums are a type of chewing gum that deliver nicotine to the body. It's a type of nicotine replacement therapy (NRT) that is often used to help people stop smoking. The nicotine is absorbed through the lining of the mouth and helps to reduce the physical withdrawal symptoms and cravings when someone stops smoking.

Category

Nicotine replacement therapy

Molecular Formula

C10H14N2

Mechanism of Action

Nicotine from the gum mimics the effects of nicotine from cigarettes, binding to nicotine receptors in the brain and partially stimulating them, thereby reducing nicotine craving and withdrawal symptoms.

Evidence Grade

A

Other Names

• Nicorette
• Nicotinell
• Nicogum

Primary Benefits

• Reduces withdrawal symptoms when quitting smoking
• Helps curb cravings for nicotine
• Can improve the success of smoking cessation programs

Recommended Dosage

Side Effects

• Mouth or throat irritation
• Upset stomach
• Increased heart rate

Precautions

• Consult with healthcare provider before use if you have heart disease, high blood pressure, or are pregnant or breastfeeding
• Do not use alongside other forms of nicotine replacement therapy unless directed by a healthcare provider

Interactions

• Certain medications like adenosine, antipsychotics, and beta blockers may interact with nicotine gums

Key References

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2446450/
• https://www.ncbi.nlm.nih.gov/books/NBK64214/