nitrate

No summary available for this substance.

Nitrate

Nitrate is a naturally occurring compound found in a variety of foods, particularly vegetables such as beetroot and spinach. It is also available as a dietary supplement. Inside the body, nitrate is converted into nitric oxide, a molecule that plays a critical role in vascular health by improving the function of the inner lining of blood vessels.

Category
Dietary Supplement
Molecular Formula
NO3-
Mechanism of Action
Nitrates are converted to nitrites by bacteria in the mouth. These nitrites then enter the circulation and are converted to nitric oxide (NO), a potent vasodilator, under conditions of low oxygen availability.
Evidence Grade
B - Moderate evidence for health benefits

Other Names

  • Potassium Nitrate
  • Sodium Nitrate
  • Nitrate salts

Primary Benefits

  • Improves cardiovascular health
  • Enhances exercise performance
  • Lowers blood pressure

Recommended Dosage

Amount 300-600 mg
Frequency 1-2 times daily
Note Dosage can vary based on individual health needs and product formulations

Side Effects

  • Headache
  • Dizziness
  • Upset stomach

Precautions

  • Not recommended for people with low blood pressure
  • Should be used under medical supervision in people with cardiovascular conditions

Interactions

  • May interact with medications for high blood pressure
  • May interact with erectile dysfunction drugs like sildenafil

Key References

  • Larsen, F.J., et al., 'Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans', Cell Metabolism, 2011
  • Webb, A.J., et al., 'Acute Blood Pressure Lowering, Vasoprotective, and Antiplatelet Properties of Dietary Nitrate via Bioconversion to Nitrite', Hypertension, 2008
Dr. Peter Attia on Mastering Longevity – Insights on Cancer Prevention, Heart Disease, and Aging
Proactive Health Strategies: Preventing Chronic Conditions Through Lifestyle Choices 3:32:40 0
“green shakes help him so like tons of like nitrates so a bunch of like green vegetables and these are like nasty tasting shakes these aren't like good tasting”

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Gary Brecka: The TRUTH About Biohacking, Light Therapy, and Nutrients
Optimizing Health: Lifestyle, Nutrition, Sleep, Exercise, and Social Connections 1:01:04 0
“trazodone and zum nitrate diazapam a lot of these will actually block the brain's view of blood oxygen essentially shut off the monitoring system and then it allows them to get into a deep sleep but they're not actually sleeping they're suffocating”

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Everything You Need To Know About Supplements, Cardio, and Metabolism | Dr. Eric Trexler
Insights on Managing Metabolism, Weight, Diet, Exercise, and Sleep 1:59:05 0
“Arginine kind of sucks I you know just because there's Alternatives that are clearly tier 2 like what uh so like instead of Argin you would just go straight to Citrine or nitrate.”

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The Truth About Microplastics – Dr Rhonda Patrick
Understanding Microplastics and Toxin Exposure in Everyday Health and Environment 1:30:09 0
“the nitrates you know are something that's found in plants they're in vegetables they're in Greens they're you know all over in nature they can also be converted into um nitrites and then ultimately n amines however vitamin C prevents the conversion so vitamin C is also found in plants so packaged together so that's why when you eat you know a lot of plants or like beets have a lot of nitrates you know beet beetroot juice extract is high in nitrates but it's also high in vitamin C and when you have the vitamin C there it converts the nitrates into nitric oxide”

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No.1 Nitric Oxide Expert: This is the anti-aging cure no one is talking about!
Unlock the secret to staying youthful with this powerful cure. 47:11 0
“oral production of nitride and nitric oxide being produced in the acid environment of the stomach is somehow regulating resistance arteries in dilation to normalize systemic blood pressure”

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No.1 Nitric Oxide Expert: This is the anti-aging cure no one is talking about!
Unlock the secret to staying youthful with this powerful cure. 1:08:24 0
“most of the bead products the desiccated bead powders provided zero nitric oxide benefit they didn't contain any nitrate no nitrite they were just we called them dead beats”

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No.1 Nitric Oxide Expert: This is the anti-aging cure no one is talking about!
Unlock the secret to staying youthful with this powerful cure. 1:10:55 0
“you really can't eat enough beets to get enough nitrate to improve your performance and the other caveat is that if you're using mouthwash you've got fluoride in your toothpaste or fluoride in your drinking water that you're mixing the beet powder in you're not going to get a nitric oxide benefit from it”

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Dr. Robert Lustig: How Sugar & Processed Foods Impact Your Health
Understanding the Complex Relationship Between Nutrition and Metabolic Health 1:00:00 0
“fructose nitrates tight Junction proteins causing them to be transiently permeable allowing some of the junk in your intestine to get through into your bloodstream.”

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