PI3 kinase inhibitor

No summary available for this substance.

PI3 kinase inhibitor

PI3 kinase inhibitors are a class of medication that works by blocking the action of PI3 kinases, a type of enzyme that plays a significant role in cell functions such as growth, proliferation, differentiation, motility, survival and intracellular trafficking. They are mainly used in the treatment of various types of cancers.

Category: Cancer Treatment
Molecular Formula: Variable, depends on the specific inhibitor
Mechanism of Action: Inhibits the PI3 kinase pathway, reducing the growth and survival of cancer cells
Evidence Grade: A

Other Names

Phosphoinositide 3-kinase inhibitor
PI3K inhibitor

Primary Benefits

Inhibits cancer cell growth
Promotes cancer cell death
Prevents cancer proliferation

Recommended Dosage

Adult	Variable, depends on the specific drug and individual patient characteristics
Children	Not typically recommended for children

Side Effects

Nausea
Fatigue
Diarrhea
Skin rash
Increased blood sugar levels

Precautions

Monitor blood glucose levels
Not suitable for pregnant or breastfeeding women
Monitor liver function

Interactions

Can interact with other medications like anticoagulants
May have interactions with certain foods

Key References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970431/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067985/

Joe Rogan Experience #1735 – Peter Attia

Nutrition, exercise, genetics, disease prevention, and health discussion highlights. 1:49:25 ⁰

“when you combine a ketogenic diet with a pi3 kinase inhibitor at least in animal studies which is about the extent of where this has been studied so far the results look really good because pi3 kinase inhibitors by themselves have not panned out even though theoretically they should be amazing for cancer”

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