Piceatannol
Piceatannol is a stilbenoid, a type of natural phenol, and a phytoalexin. It is derived from resveratrol, a compound found in the skin of red grapes, and is known for its anti-inflammatory, antioxidant, and anti-cancer properties. It's often studied for its potential benefits in cardiovascular health, cancer prevention, and neuroprotection.
- Category
- Phytochemical
- Molecular Formula
- C14H12O4
- Mechanism of Action
- Piceatannol inhibits the activity of certain enzymes involved in inflammation and cell proliferation, such as cyclooxygenase and kinase enzymes. It also displays antioxidant activity by neutralizing harmful free radicals, and has been shown to induce cell cycle arrest and apoptosis in cancer cells.
- Evidence Grade
- C - Promising preliminary evidence, but more research needed
Other Names
- Astringinin
- Pinosylvin monomethyl ether
- 3,4,3',5'-Tetrahydroxy-trans-stilbene
Primary Benefits
- Anti-inflammatory properties
- Antioxidant activity
- Potential anti-cancer effects
- Neuroprotective effects
Recommended Dosage
| Adults |
There is no established recommended dosage for piceatannol. It is usually consumed as part of a balanced diet through foods rich in this compound, such as grapes and berries. |
Side Effects
- Allergic reactions
- Possible hormonal disruption
- Potential interference with certain medications
Precautions
- Pregnant and lactating women should avoid use
- People with hormone-sensitive conditions should use with caution
Interactions
- May interact with anticoagulant medications
- May interact with drugs metabolized by certain liver enzymes
Key References
- Piceatannol, Natural Polyphenolic Stilbene, Inhibits Fat Accumulation in Mice - PubMed
- Piceatannol: a natural stilbene for mental and physical health - PubMed
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