Serotonin Drugs
Serotonin drugs, also known as Selective Serotonin Reuptake Inhibitors (SSRIs), are a type of antidepressant that work by increasing levels of serotonin in the brain. Serotonin is a neurotransmitter that carries signals between brain cells. SSRIs block the reabsorption (reuptake) of serotonin into neurons, making more serotonin available. SSRIs are called 'selective' because they mainly affect serotonin, not other neurotransmitters.
- Category
- Pharmaceutical
- Molecular Formula
- Varies per specific drug
- Mechanism of Action
- Blocks the reabsorption of serotonin into neurons, increasing the level of serotonin in the brain.
- Evidence Grade
- A
Other Names
- SSRIs
- Selective Serotonin Reuptake Inhibitors
Primary Benefits
- Depression treatment
- Anxiety disorder treatment
- Obsessive-compulsive disorder treatment
Recommended Dosage
| Min |
Depends on the specific drug and individual's health condition |
| Max |
Depends on the specific drug and individual's health condition |
| Unit |
mg/day |
Side Effects
- Nausea
- Nervousness
- Insomnia
- Sexual problems
- Drowsiness
Precautions
- Monitor for worsening depression or suicidal thoughts
- Do not stop taking suddenly
- Avoid alcohol
Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Pimozide
- Thioridazine
- St. John's wort
Key References
- https://www.mayoclinic.org/diseases-conditions/depression/in-depth/ssris/art-20044825
- https://www.nhs.uk/conditions/ssris-selective-serotonin-reuptake-inhibitors/
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