Shingles Vaccines
Shingles vaccines are immunizations that reduce the risk of developing shingles, a painful skin rash caused by the varicella-zoster virus (VZV), which also causes chickenpox. There are two primary types of shingles vaccines: Zostavax and Shingrix.
- Category
- Vaccine
- Molecular Formula
- Not applicable
- Mechanism of Action
- The vaccines stimulate the immune system to produce a specific immune response against the varicella-zoster virus.
- Evidence Grade
- A
Other Names
- Herpes Zoster Vaccine
- VZV Vaccine
Primary Benefits
- Reduces the risk of shingles
- Decreases the severity and length of the illness
- Prevents postherpetic neuralgia (PHN)
Recommended Dosage
| Zostavax |
Single dose for individuals 60 years and older |
| Shingrix |
Two doses, 2-6 months apart for individuals 50 years and older |
Side Effects
- Pain, redness, or swelling at the injection site
- Headaches
- Fever
Precautions
- Not recommended for individuals with weakened immune systems
- Not recommended for individuals who are pregnant or trying to become pregnant
Interactions
- Immunosuppressive therapies
- Antiviral medications
Key References
- Harvard Health Publishing: Shingles Vaccine: Should I Get It?
- CDC: Shingles Vaccination
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