valine

No summary available for this substance.

Valine

Valine is an essential amino acid, meaning it cannot be produced by the body and must be obtained through the diet. It is one of three branched-chain amino acids (BCAAs), alongside leucine and isoleucine, known for their role in muscle development and repair.

Category
Amino Acid
Molecular Formula
C5H11NO2
Mechanism of Action
Valine is utilized in the body for muscle growth and repair, energy production, and as a precursor for the synthesis of other important molecules.
Evidence Grade
C

Other Names

  • 2-amino-3-methylbutanoic acid

Primary Benefits

  • Supports muscle growth and repair
  • Enhances energy production
  • Aids in maintaining a healthy immune system

Recommended Dosage

Adults 10 to 20 grams per day
Children Depends on age and weight

Side Effects

  • Nausea
  • Hallucination
  • Uncoordinated movements

Precautions

  • People with kidney or liver disease should avoid excessive intake
  • Pregnant or breastfeeding women should consult a healthcare professional before use

Interactions

  • Levodopa
  • Antipsychotics

Key References

  • 'Branched-Chain Amino Acids and Brain Function' - Journal of Nutrition, June 2005
  • 'Valine, an essential amino acid: characterization, metabolism and application' - International Journal of Molecular Sciences, 2020
REVERSE AGING: What To Eat & When To Eat For LONGEVITY | David Sinclair
Enhance Health, Longevity, and Disease Prevention with Lifestyle Choices 1:02:18 0
“just mostly from plant-based sources where there's not a lot of the branched chain amino acids those leucine isoleucine valine amino acids are the ones that activate mtor”

No comments yet.

View all comments (0)
Protein Amount, Quality and Timing – with Dr. Donald Layman | The Proof Podcast EP 236
Optimal Protein Intake for Health and Muscle Function Explained 1:01:33 0
“all of this is the branch chain amino acid leucine for years since the 1930s we've known that the branch chain amino acids are not metabolized in liver all of the other amino acids are metabolized in liver but these three branch chain leucine, valine and isoleucine get sent out primarily to skeletal muscle so the body has learned to sense it it is senses it as a indicator of protein coming in and basically when that leucine concentration goes up from basically fasting levels to about three times fasting levels uh it triggers a complex inside muscle known as mtor and that's the main sort of Central regulatory function that triggers all these sort of initiation factors and we trigger maximum protein synthesis.”

No comments yet.

View all comments (0)
What to Eat & When to Eat for Longevity | Lifespan with Dr. David Sinclair #2
Optimal dietary choices and habits for longevity and health benefits 46:00 0
“So, now you've got these amino acids circling in your body, circulating, and there are three ones that are particularly important to know about, it's leucine, ISO leucine and valine also known as the branched-chain amino acids.”

No comments yet.

View all comments (0)