Understanding Metabolic Health: Risks, Dysfunction, and Dietary Recommendations

Nutrition 0:12 0
“the biggest mistake we're making is we're eating Ultra processed food”

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Metabolic health 0:54 0
“we talked about metabolic Health metabolic dysfunction what causes metabolic dysfunction and how to correct it”

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Metabolic health 1:06 0
“if metabolic dysfunction also known as insulin resistance is causing us to be sick, what's causing that and how do we reverse it”

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Environment 2:48 0
“we were learning all about cardiovascular health um and all the pharmacology and physiology of you know heart disease which is the number one killer in the United States in a window dark Subterranean room where we sat for 8 hours a day”

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Metabolic health 5:37 0
“there is a set of core physiologic disturbances caused by our modern diet and environment that are destroying our foundational metabolic Health the way we make energy in our cells and this is showing up in our 200 different cell types as all these different diseases”

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Metabolic health 5:49 0
“it's what I call the trifecta of metabolic dysfunction or bad energy oxy of stress chronic inflammation mitochondrial dysfunction these invisible processes that we don't learn about we don't really have good tests for that are happening”

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Environment 6:42 0
“all the reasons we're sick they're environmental it's food, it's our diet, it's our lifestyle, it's we're sitting too much, we're not seeing sunlight, we're exposed to all these unregulated toxins”

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Nutrition 7:53 0
“how many nutrition classes did you have at Stanford Medical School? Zero.”

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Nutrition 11:21 0
“like an anti-inflammatory diet for an inflammatory condition that we're treating with steroids and surgery”

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Nutrition 12:25 0
“you're basically the nutrition wacko who you thinks you're too good for all of this and you're questioning the Dogma”

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Disease prevention 19:59 0
“almost every single condition I'm treating in my specialty is an inflammatory condition and the only tools I'm using are drugs and surgery and yet drugs and surgery can't do anything to change the physiology that's leading to inflammation in the first place and what I'm doing is not doing anything to affect the root causes”

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Metabolic health 23:07 0
“if everything is metabolic dysfunction and by everything I'm sort of saying that yeah H that's a little bit of hyperbole right because there are certain like single nucleotide polymorphisms that create like CLE cell anemia and that's probably not that's not caused by the environment there are genetic things H disease there are toxins in the environment if the vast majority of the chronic diseases chronic disease that most of us suffer from that affect our quality of life our children's quality of lives our parents quality of lives if this is mostly metabolic dysfunction what causes it and how do we reverse it”

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Metabolic health 25:29 0
“evidence is showing us that about 93.2% of American adults have metabolic dysfunction have this underpowering fundamental issue and that what's causing that is is usually some Confluence of what I mentioned before the mitochondria that actually make the energy being damaged this machine that makes the power makes the gas has a problem functioning that can be to a lot of different things that underpowering and distress leads the immune system to get revved up because what could be more inflammatory to a body than cells that can't do their work they're sending out distress signals and then the immune system tries to help but the immune system can't help because it's the problem is caused by the environment they can't take the doughnut out of your hand and so you get this stew of chronic inflammation trying to help these distressed underpowered cells but they're impotent in the face of the threats and then you have this other thing oxy of stress that's basically the damage mitochondria that can't do their work properly send out exhaust and sort of you know create damaging byproducts um that that cause essentially like a a chain reaction of Destruction in the…”

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Nutrition 26:53 0
“it's our diet”

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Sleep 26:59 0
“it's our lack of sleep”

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Exercise 26:59 0
“it's our incredibly sedentary Behavior”

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Stress management 27:06 0
“it's chronic stress so psychological stress and poor emotional health”

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Toxin exposure 27:06 0
“it is environmental toxins”

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Circadian rhythm 27:12 0
“it is our modern relationship with light so circadian see or circadian disruption based on our new relationship with sunlight and artificial light”

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Environment 27:20 0
“it's issues with how we relate to temperature um so the fact that we live a Thermon neutral existence now we're all at 72 degrees and we don't have thermal stimuli to promote metabolic health”

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Gut health 27:31 0
“and certainly microbiome issues which is kind of tied to food but also separate from food because there's a lot of other things destroying our microbiome”

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Substances 27:36 0
“it's the medications we're taking it's the it's the total and utter overuse of over-the-counter and prescription medications many of which directly cause mitochondrial dysfunction oxidative stress”

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Environment 29:06 0
“the world we're living in and choosing to live in today is not conducive to functional human cellular biology full stop.”

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Environment 30:31 0
“a lot of the things we've invented under the sake of innovation and comfort are actually destroying our cellular biology.”

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Mental health 33:21 0
“depression and anxiety we all it's like it's through the roof suicide is just it's so disastrously high as one of the leading causes of death in the US”

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Nutrition 37:04 0
“Ultra processed foods are a science experiment invented by food chemists and food scientists uh pretty much just starting after World War II started really accelerating in use in the 1970s and just simply put they are a science experiment that has failed it's not working they're not conducive to Cellular bi human cellular biology and they're very bad for the planet as well.”

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Nutrition 38:04 0
“Ultra processed foods have significantly less micronutrients than real food so during the processing where you take a whole food and you modulate it so so much to turn it into these individual components that then get put back together like a Frankenstein to make this thing that looks like food if you really squint or from 100 feet might look like food but actually is really just chemicals put together and shaped and colored and things like that.”

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Nutrition 39:52 0
“we have 10,000 food chemicals allowed in the US most of which have never been studied for safety”

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Nutrition 41:36 0
“Europe has only 400 [food additives].”

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Nutrition 42:21 0
“67% of calories come from Ultra processed foods.”

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Nutrition 44:28 0
“Ultra processed foods drive us to eat more calories.”

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Nutrition 45:56 0
“the ultr processed food is literally designed to make us eat more calories and be insatiable on top of the fact so you get people eating more food the food is not then supporting on the cellular level the actual processing of that food because it's micronutrient poor and it's very destructive to our cellular biology with all the food additives.”

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Nutrition 46:51 0
“Ultra processed foods like fro Loops they are different recipes than we're using overseas because overseas they have stricter Health standards for what you can feed to Children you can't feed them artificial many of the artificial food dies like red 40 so they use vegetable extracts and they use like they literally use turmeric powder in some countries to to to color fro loops and here we're using petroleum based synthetic dyes that we know are linked to um ADHD and other uh issues with neurologic development.”

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Nutrition 50:00 0
“the quickest way aside from all dietary Dogma to get the body the best chance of getting the molecular building blocks to 3D print a functional body is to eat real food and not just to eat real food but to eat the freshest food possible because every day that the food is dead either the animal is killed or the food is taken out of the ground it's denaturing it's you're losing some of that those magical molecules that can work with our biology to create function.”

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Metabolic health 51:49 0
“understand the labs that can give you a hint about your metabolic health so things like the you know apob fasting insulin fasting glucose triglycerides htl cholesterol hscrp an inflammatory marker uric acid vitamin D um I think I said fasting insulin um if you can look at these things every few months and actually be certain that you are like really in the optimal range for a lot of these things and you feel incredible you're probably eating the right diet”

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Nutrition 52:21 0
“you're probably eating the right diet you don't actually need someone to tell you you need to be vegan you need to be Carn you need to be paleo you need to be keto you need to be this or that because if you are eating a Whole Food's diet and your labs are looking perfect and you feel freaking incredible you're probably for this moment in time in a good place”

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Nutrition 56:51 0
“they're designed to make you eat more and they're probably breaking your mitochondria which makes it so that you can't actually turn that food energy into usable energy.”

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Nutrition 57:30 0
“seed oils are destroying our planet... they are pretty much universally being grown as monocrop commodity crop agriculture just ruthlessly sprayed with toxic pesticides.”

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Nutrition 58:39 0
“the process through which they're made is disgusting... involves chemical solvents like hexanes and heating the oil to very high heat, bleaching the oil.”

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Nutrition 1:00:49 0
“seed oils... they're very enriched in Omega 6... potentially inflammatory in their own right because they incorporate into cell membranes and when your immune cells are coming around trying to make prostaglandins and other immune compounds, when they snip omega-6s it turns into pro-inflammatory immune mediators.”

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Nutrition 1:02:58 0
“you're putting a bunch of linolic acid this gets a little technical but my audience I think has heard it so you're putting this omega-6 18 carbon polyunsaturated fatty acid into your cells”

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Nutrition 1:03:23 0
“if we ate seven tablespoons fish oil per day that might be a problem for humans right there are actually studies in Eskimos who eat lots of fish that like there we can exceed the amount of Omega-3s that we want it can lead to potential clotting issues and maybe even hemorrhagic strokes”

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Nutrition 1:04:09 0
“seed oils accumulate so they might not cause problems the day you eat them and that's kind of this loophole that people who want to argue and say seed oils are neutral or they're benign um or they're even sometimes positive leaning in the in statistics we say look well they don't cause inflammation in the short term but like if you stack your cells full of omega-6 linolic acid which is by the way the most common uh fatty acid in LDL particles is is omega-6 is linolic acid”

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Nutrition 1:04:54 0
“there's studies in humans that are random IED and controlled and they show that oxidized LDL goes up when you eat seed oils and LP littlea goes up when you eat seed oils”

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Gut health 1:08:17 0
“the microbiome eats polyphenols and fiber and then it's going to have a pro effect through the short chain fatty acids they create”

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Nutrition 1:08:32 0
“a tablespoon of refined sugar that has no polyphenols, no antioxidants, no micronutrients, no vitamins and minerals, no fiber, nothing; it's just a straight up it's a drug that's what it is”

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Metabolic health 1:08:58 0
“a whole fruit you can't really get addicted to whole fruit cuz it doesn't it absorbs so slowly and the way that interacts with our satiety hormones it doesn't activate the dopamine pathway the same way a refined sugar does”

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Metabolic health 1:09:31 0
“my reaction in terms of blood glucose response to different fruits is very variable”

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Metabolic health 1:10:59 0
“postprandial hypoglycemia there was a paper in nature from a couple years ago that showed extent of our post Spike crashes and glucose predicts how much energy we're actually going to try and consume that day”

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Nutrition 1:13:56 0
“if I live in Seattle should I just be eating squash all winter like maybe I shouldn't be eating strawberries”

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Nutrition 1:14:16 0
“you'd be eating your root vegetables throughout the winter your onions and your potatoes and they would last for a long time”

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Nutrition 1:14:27 0
“certain fruits actually can last for a long time especially when stored properly”

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Nutrition 1:14:33 0
“the fermented foods right because they'd be fermenting and processing in the Indigenous way you know to basically preserve nutrients for the winter”

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Nutrition 1:15:25 0
“if we want to eat more during sunlight hours then we may need to eating our dinner at different times in the summer versus the winter because we know that like once that melatonin starts getting secretion it does impact our insulin sensitivity”

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Nutrition 1:19:42 0
“I've been impressed with honey, you know I mean I think there are trials that it actually raises testosterone in males.”

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Nutrition 1:19:47 0
“There's actually a really interesting trial in diabetics that I've cited a lot where they gave people honey up to I think 125 gram a day and over that time so what happened their blood sugar goes up a little bit I think A1C went up um a small amount I think the average blood sugar difference between the honey and non-honey groups was about maybe 10 milligrams per deciliter so the A1C went up but the um the fasting glucose went down.”

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Nutrition 1:22:41 0
“I think for the average American body is like we have to get off all the ultr processed foods so that we're not overwhelming our cellular Machinery every single day with toxins and these just super nutrient-dense Foods so that our because our cells know how to clear themselves out they know how to turn over and get to functionality but we just have to Full Stop on the like the toxic crap coming in.”

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Nutrition 1:24:20 0
“the local is key more nutrients to help your cells heal the average piece of food in the US is traveling 1500 miles we have to cut that down to 100 miles I think um and eat the food from the farmers market”

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Nutrition 1:24:44 0
“real food as local as possible if you do those two things and just commit to cut out all the ultra processed food your life will transform”

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Nutrition 1:25:05 0
“if you still have issues once you're doing the real food then go down the further rabbit holes and get more selective with therapeutic diet”

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Nutrition 1:25:31 0
“there's a lot of people who have truly healed their gut from getting rid of all the plant compounds”

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Sleep 1:30:23 0
“I think for me it's food and sleep are the biggest ones but that's just my perspective so let's talk about sleep for a minute to talk people about this I mean sleep we're not sleeping well in this culture.”

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Circadian rhythm 1:30:48 0
“our circadian rhythms are destroyed because of artificial light and we just don't go in the sunlight anymore which so sleep and sunlight I think are very interconnected.”

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Environment 1:30:55 0
“the average American now is spending 93% of their time indoors it's crazy and that that was a study that about 4% of that is in cars and the rest is in the four walls of your house.”

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Sleep 1:32:41 0
“our sleep is short we are not sleeping enough we are not sleeping consistently meaning we are not going to bed and waking up at regular times and if we did live by the sun we would have these you know periods that we sleep and it would change seasonally but it would be pretty specific you know it's only changing Maybe by a minute or two each day as as maybe the sun changes.”

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Sun protection 1:35:01 0
“you're doing indoors that you could actually do outdoors because the more sunlight you get during the day the easier it's going to be to go to sleep at night and the higher quality your sleep is going to be”

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Sleep 1:35:11 0
“humans are sleeping very erratic bed times and wake up times and there's this concept called social jet lag which is a scientific term where basically if you look at work days and Leisure Days so like weekdays and weekends and obviously that varies for different people working different shifts if you are if you look at how you sleep like 12 12 midnight to 8:00 a.m your sleep midpoint is 4:00 a.m. and if you're sleeping 10:00 p.m. to 6: a.m. your sleep midpoint is 2 am.”

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Disease prevention 1:35:46 0
“if the midpoint of your sleep between your work days and your leisure days or just between different days of the week is over two hours it like doubles your risk of developing diabetes”

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Circadian rhythm 1:36:57 0
“this probably won't mess up my circadian rhythm too much we're going to walk right outside and go for a walk right now and meet our friend Anthony Gustin so we're going to get outside move and do all the things because we've been sitting so we're gonna hopefully correct some of this blue light”

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Sun protection 1:39:59 0
“being outside with the sun it reminds you that you're on a planet yes in a in a universe sometimes I remember that's amazing and I think it's like on that subconscious level it also reminds us it feeds into the stress component of metabolic dysfunction which is so much of the reasons we're stressed right now is because we feel I think we're living in a fear Matrix that is created to profit off of our feeling small and limited and when we get outside in the sun more often I mean I can't prove this with a double blind Placebo controlled study but like it makes us happier and healthier because we see our picture in the greater the greater web of things”

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Sun protection 1:40:41 0
“when I was in Seattle in my residency in Psychiatry we had um these Bright Lights you know because Seattle's quite dark in the winter and I saw a lot of people with Seasonal effective disorder and the bright lights don't really work right it's just a blue light that you're putting in front of your eyes and it doesn't work but what would work is if somebody would go to Mexico and actually get in the Sun and so or if somebody would actually go outside and you can give someone vitamin D for season doesn't work it doesn't work doesn't work what if someone in Seattle even though it's dark in the winter just basically spends like almost all their time Outdoors that would probably help it would help a lot because you're getting”

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Most important takeaways of the video

  1. Ultra-processed foods are highlighted as a significant dietary mistake, with a call to avoid them due to their negative impact on health and cellular biology.
  2. The discussion emphasizes the importance of metabolic health, exploring the causes and solutions for metabolic dysfunction, particularly insulin resistance, and its link to various illnesses.
  3. The impact of the environment on health is emphasized, with concerns raised about dark learning environments affecting cardiovascular health and the detrimental effects of modern lifestyles on cellular biology.
  4. Lack of nutrition education in medical training is highlighted, pointing out the gap in understanding the role of diet in health and the need for broader acceptance of nutritional approaches in medical treatment.
  5. Various factors contributing to metabolic dysfunction are discussed, including stress, chronic inflammation, mitochondrial dysfunction, sedentary

Summary of Video on Nutrition and Metabolic Health

Ultra-Processed Foods and Health Risks

The discussion highlights the significant health risks associated with the consumption of ultra-processed foods. These foods are identified as a major dietary mistake due to their low micronutrient levels and high chemical content, which negatively affect metabolic functions and overall health. It’s noted that ultra-processed foods, which began to proliferate in the 1970s, make up a substantial portion of the average diet, driving over-consumption of calories and contributing to various diseases.

Metabolic Dysfunction and Chronic Disease

Metabolic health, particularly the issue of metabolic dysfunction and its primary form, insulin resistance, is extensively discussed. The dialogue explores the root causes and potential reversals of metabolic dysfunction. Environmental factors, including diet, sedentary lifestyles, insufficient sleep, and exposure to toxins, are implicated in the prevalence of metabolic issues. Specific attention is given to mitochondrial damage and its role in chronic inflammation and oxidative stress, which further deteriorate metabolic health.

Medical Education and Practice

The lack of nutritional education in medical schools is criticized, with calls for integrating comprehensive nutrition and wellness education into medical training to better address the underlying causes of inflammatory conditions, rather than relying solely on medications and surgeries.

Environmental Impact on Health

The discussion underscores the negative impact of modern lifestyle choices facilitated by technological and industrial advancements, which are detrimental to cellular health. Factors such as artificial lighting, constant exposure to screens, and a lack of natural environments are discussed as disruptors of circadian rhythms and overall well-being.

Diet Recommendations

Practical dietary recommendations include reducing the consumption of ultra-processed foods and instead focusing on whole, fresh foods. Regular monitoring of specific health biomarkers like fasting glucose and cholesterol levels is suggested to gauge metabolic health effectively. Eating locally sourced and minimally processed foods is also encouraged to ensure the consumption of nutrient-rich diets.

Cultural and Behavioral Factors

The need for cultural shifts towards better health practices is emphasized. This includes increasing awareness of the importance of sleep, managing light exposure, and encouraging regular physical activity to align with natural circadian rhythms. The overarching message advocates for a reconnection with natural processes to combat the pervasive health issues presented by modern lifestyles.